Evidence map›Paper›PMID 22224878›Full record

ReviewAnnual review of public health2012

Preventability of cancer: the relative contributions of biologic and social and physical environmental determinants of cancer mortality.

Graham A Colditz, Esther K Wei

Registry-linked trialAbstract readReview
In one paragraph

Review in Annual review of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06931847 (SUstaiNable inteRventions and Healthy behavIours for adoleScent Primary prEvention of Cancer With Digital Tools. Study 2), which is not on this map. Cited by 64 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06931847 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

SUstaiNable inteRventions and Healthy behavIours for adoleScent Primary prEvention of Cancer With Digital Tools. Study 2: Multiple Behaviour Intervention Platform

Typeobservational_patient_registrySponsorBiobizkaia Health Research InstituteRan2025 to 2028Enrolled4,000ConditionsCancerArmsSUNRISE program
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Self-monitoring physical activity with a smartphone application in cancer patients: a randomized feasibility study (SMART-trial).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Trial
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Assessing Cancer Knowledge among Health Students in Portugal.Portuguese journal of public health · 2025
    Article
  15. Enhancing the Impact of Digital Therapeutics in Cancer Prevention: Reflections on Recent Findings.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Graham A ColditzAlvin J. Siteman Cancer Center and Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63108, USA. colditzg@wustl.edu
Esther K Wei

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI David G DeNardo · 2001 to 2026
$128.0M
Prostate Cancer Survivor Outreach and Education Message Testing StudyU01CA114594 · NCI · WASHINGTON UNIVERSITY · PI COLDITZ, GRAHAM A. · 2005 to 2009
$2.2M
NCI NIH HHS P30 CA091842NCI NIH HHS U01 CA114594
6 · The paper itself

Abstract

Whereas models of cancer disparities and variation in cancer burden within population groups now specify multiple levels of action from biologic processes to individual risk factors and social and physical contextual factors, approaches to estimating the preventable proportion of cancer use more traditional direct models often from single exposures to cancer at specific organ sites. These approaches are reviewed, and the strengths and limitations are presented. The need for additional multilevel data and approaches to estimation of preventability are identified. International or regional variation in cancer may offer the most integrated exposure assessment over the life course. For the four leading cancers, which account for 50% of incidence and mortality, biologic, social, and physical environments play differing roles in etiology and potential prevention. Better understanding of the interactions and contributions across these levels will help refine prevention strategies.

Indexed as

Environmental ExposureRisk AssessmentHealth Status DisparitiesHumansModels, BiologicalNeoplasmsRisk Factors

Identifiers

PMID22224878
PMCPMC3631776

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.