Evidence map›Paper›PMID 22224593›Full record

ArticleGenetic testing and molecular biomarkers2012

Donation intentions for cancer genetics research among African Americans.

Jasmine A McDonald, Benita Weathers, Frances K Barg, Andrea B Troxel, Judy A Shea, Deborah Bowen, Carmen E Guerra, Chanita Hughes Halbert

Abstract read
In one paragraph

Article in Genetic testing and molecular biomarkers, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Equity in Genomic Medicine.Annual review of genomics and human genetics · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Strategies for enrollment of African Americans into cancer genetic studies.Journal of cancer education : the official journal of the American Association for Cancer Education · 2015
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jasmine A McDonaldCenter for Community-Based Research and Health Disparities, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Benita Weathers
Frances K Barg
Andrea B Troxel
Judy A Shea
Deborah Bowen
Carmen E Guerra
Chanita Hughes Halbert
University of Pennsylvania · USBoston University · USUniversity of Pennsylvania Health System · US

Funding

Penn Center for ELSI Research in Emerging Genetic Technologies in Health CareP50HG004487 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI PYERITZ, REED E · 2007 to 2012
$6.2M
African American Participation in Cancer Genetics ResearchR01HG004346 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI HUGHES-HALBERT, CHANITA A. · 2007 to 2009
$1.2M
NHGRI NIH HHS P50HG004487NHGRI NIH HHS R01HG004346
6 · The paper itself

Abstract

aimsScientific agencies rely on individuals to donate their DNA to support research on chronic conditions that disproportionately affect African Americans; however, donation is variable in this population. The purpose of this study was to identify sociodemographic characteristics, health care variables, and cultural values having significant independent associations with intentions to donate blood or saliva samples for cancer genetics research among African American adults.

methodCross-sectional survey of donation intentions.

resultsThe majority of respondents (73%) were willing to donate a biological sample for cancer genetics research. The results of the multivariate regression model found that respondents who received care at a facility other than a doctor's office (e.g., community center) were about five times more likely to be willing to donate a sample for cancer genetics research (odds ratio [OR]=5.28, 95% confidence interval [CI]=1.16-24.12, p=0.03); whereas, greater levels of religiosity (OR=0.09, 95% CI=0.01-0.75, p=0.02) and present temporal orientation (OR=0.23, 95% CI=0.06-0.79, p=0.02) were associated with a lower likelihood of donating a sample.

conclusionEfforts to enhance donation of biological samples for cancer genetics research may need to target diverse clinical sites for recruitment. Additionally, recruitment materials may need to address cultural values related to religiosity and present temporal orientation.

Indexed as

Genetic ResearchIntentionAdultAttitude to HealthBlack or African AmericanBloodCultural CharacteristicsFemaleHumansInterviews as TopicMaleNeoplasmsSalivaSocioeconomic FactorsTissue Donors

Identifiers

PMID22224593
PMCPMC3326272
OpenAlexW1998053647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.