Evidence map›Paper›PMID 22223765›Full record

GuidelineThe Journal of clinical endocrinology and metabolism2012

Management of hyperglycemia in hospitalized patients in non-critical care setting: an endocrine society clinical practice guideline.

Guillermo E Umpierrez, Richard Hellman, Mary T Korytkowski, Mikhail Kosiborod, Gregory A Maynard, Victor M Montori, Jane J Seley, Greet Van den Berghe, Endocrine Society

5 registry-linked trialsOpen access · bronzeAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in The Journal of clinical endocrinology and metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 409 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
409citing papers in PubMed, 11 pooled it
63.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06187285 nacompletedstarted 2024, after this paper: background citation

Efficay and Safety of Empagliflozin Versus Sitagliptin for the In-patient Management of Hyperglycemia: Randomised Control

Ran2024Enrolled220Registered outcomes10Posted comparisons0ConditionsType 2 DiabetesArmsempagliflozin 25 mg, Sitagliptin 100mg
PMID 11588337PMID 11794168PMID 11889147PMID 12105309PMID 9527963PMID 37380728PMID 33915345PMID 27964837PMID 19429873other papers from this trial
Open the trial in the graph
NCT00911625 phase4completednot on this map

Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency

TypeinterventionalSponsorLoyola UniversityRan2009 to 2011Enrolled114ConditionsType 2 Diabetes, Renal InsufficiencyArms0.5 units/kg daily insulin, 0.25 units/kg daily insulin
NCT01648218 phase4terminatednot on this map

Insulin Therapy for Post-transplant Glucocorticoid Induced Hyperglycemia

TypeinterventionalSponsorVancouver General HospitalRan2012 to 2013Enrolled5ConditionsPost-Transplant Glucocorticoid Induced DiabetesArmsNeutral protamine hagedorn (NPH) insulin, Regular human insulin or Insulin Aspart, Insulin glargine
NCT05752929 phase4completednot on this mapstarted 2016, after this paper: background citation

Comparison of 2 Hyperglycemia-correction Scales in Hospitalized Patients in an Institution in Bogotá, Colombia

TypeinterventionalSponsorHospital Universitario Clinica San RafaelRan2016 to 2019Enrolled116ConditionsDiabete Type 2, HyperglycemiaArmsInsulin, insulin
NCT06206525 nacompletednot on this mapstarted 2024, after this paper: background citation

Feasibility Trial Using an Insulin Dosing Calculator for Patients With Type 2 Diabetes Mellitus on Hospital Admission

TypeinterventionalSponsorUniversity of WashingtonRan2024 to 2025Enrolled38ConditionsDiabetes Mellitus, Type 2ArmsInitial insulin dosing calculator
3 · Its place in the literature

Who cites it

409 citing papers in PubMed, 11 syntheses or guidelines pooled it, 1,115 citations in OpenAlex.

  1. Pooled it
  2. [Hospital diabetes management (Update 2026)].Wiener klinische Wochenschrift · 2026
    Guideline
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Glucocorticoid-Induced Hyperglycemia Including Dexamethasone-Associated Hyperglycemia in COVID-19 Infection: A Systematic Review.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Pooled it
  7. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  8. Pooled it
  9. Guideline
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  11. Pooled it
  12. Trial
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349 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Guillermo E UmpierrezEmory University School of Medicine, Atlanta, Georgia 30322, USA.
Richard Hellman
Mary T Korytkowski
Mikhail Kosiborod
Gregory A Maynard
Victor M Montori
Jane J Seley
Greet Van den Berghe
Endocrine Society
Emory University · USKU Leuven · BEMayo Clinic · USNew York Hospital Queens · USSaint Luke's Hospital · USUniversity of California San Diego Medical Center · USUniversity of Missouri–Kansas City · USUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim was to formulate practice guidelines on the management of hyperglycemia in hospitalized patients in the non-critical care setting.

participantsThe Task Force was composed of a chair, selected by the Clinical Guidelines Subcommittee of The Endocrine Society, six additional experts, and a methodologist. EVIDENCE: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. CONSENSUS PROCESS: One group meeting, several conference calls, and e-mail communications enabled consensus. Endocrine Society members, American Diabetes Association, American Heart Association, American Association of Diabetes Educators, European Society of Endocrinology, and the Society of Hospital Medicine reviewed and commented on preliminary drafts of this guideline.

conclusionsHyperglycemia is a common, serious, and costly health care problem in hospitalized patients. Observational and randomized controlled studies indicate that improvement in glycemic control results in lower rates of hospital complications in general medicine and surgery patients. Implementing a standardized sc insulin order set promoting the use of scheduled basal and nutritional insulin therapy is a key intervention in the inpatient management of diabetes. We provide recommendations for practical, achievable, and safe glycemic targets and describe protocols, procedures, and system improvements required to facilitate the achievement of glycemic goals in patients with hyperglycemia and diabetes admitted in non-critical care settings.

Indexed as

HospitalizationBlood Glucose Self-MonitoringContinuity of Patient CareCritical CareEndocrinologyEvidence-Based PracticeHumansHyperglycemiaHypoglycemic AgentsInpatientsInsulinIntraoperative CareMonitoring, PhysiologicSocieties, MedicalHypoglycemic AgentsInsulin

Identifiers

PMID22223765
OpenAlexW2144913975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.