Evidence map›Paper›PMID 22223599›Full record

ArticleGenesis (New York, N.Y. : 2000)2012

Identification of novel microRNAs in Xenopus laevis metaphase II arrested eggs.

Sakthikumar Ambady, Zheyang Wu, Tanja Dominko

Abstract read
In one paragraph

Article in Genesis (New York, N.Y. : 2000), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sakthikumar AmbadyDepartment of Biomedical Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. sambady@wpi.edu
Zheyang Wu
Tanja Dominko

Funding

De-Differentiating Adult Human Fibroblasts into Stem-Like Cells Using ConditionsR01GM085456 · NIGMS · WORCESTER POLYTECHNIC INSTITUTE · PI DOMINKO, TANJA · 2008 to 2010
$981k
NIGMS NIH HHS R01 GM085456NIGMS NIH HHS R01GM085456.
6 · The paper itself

Abstract

Using a combination of deep sequencing and bioinformatics approach, we for the first time identify miRNAs and their relative abundance in mature, metaphase II arrested eggs in Xenopus laevis. We characterize 115 miRNAs that have been described either in Xenopus tropicalis (85), X. laevis (9), or other vertebrate species (21) that also map to known Xenopus pre-miRNAs and to the X. tropicalis genome. In addition, 72 new X. laevis putative candidate miRNAs are identified based on mapping to X. tropicalis genome within regions that have the propensity to form hairpin loops. These data expand on the availability of genetic information in X. laevis and identify target miRNAs for future functional studies.

Indexed as

AnimalsComputational BiologyFemaleGene Expression ProfilingGene Expression Regulation, DevelopmentalMetaphaseMicroRNAsOvumXenopusXenopus laevisMicroRNAs

Identifiers

PMID22223599
PMCPMC3309558

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.