Evidence map›Paper›PMID 22223206›Full record

ArticleCirculation research2012

A second chance for a PPARγ targeted therapy?

Andrew W Norris, Curt D Sigmund

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. The PPARPPAR research · 2020
    Review
  4. PPARγ and the global map of adipogenesis and beyond.Trends in endocrinology and metabolism: TEM · 2014
    Review
  5. Mechanisms of thrombosis in obesity.Current opinion in hematology · 2013
    Review
  6. Pioglitazone attenuates valvular calcification induced by hypercholesterolemia.Arteriosclerosis, thrombosis, and vascular biology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew W NorrisDepartment of Pharmacology Roy J and Lucille A Carver College of Medicine University of Iowa, Iowa City, Iowa 52242, USA.
Curt D Sigmund

Funding

Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI GROBE, JUSTIN L · 2007 to 2022
$30.2M
Vascular Protection During HypertensionP01HL062984 · NHLBI · UNIVERSITY OF IOWA · PI HEISTAD, DONALD D · 2000 to 2015
$22.2M
SIGNIFICANCE OF ANGIOTENSINOGEN VARIANTS IN HYPERTENSIONR01HL061446 · NHLBI · UNIVERSITY OF IOWA · PI SIGMUND, CURT DANIEL · 1999 to 2013
$4.8M
Role of Enhancers Regulating Renin Gene ExpressionR37HL048058 · NHLBI · UNIVERSITY OF IOWA · PI SIGMUND, CURT DANIEL · 2006 to 2015
$4.3M
TRANSGENIC STUDIES OF THE HUMAN RENIN-ANGIOTENSIN SYSTEMR01HL048058 · NHLBI · UNIVERSITY OF IOWA · PI SIGMUND, CURT DANIEL · 1993 to 2004
$1.8M
Regulatory Control of Metabolic Flexibility in Skeletal Muscle.R01DK081548 · NIDDK · UNIVERSITY OF IOWA · PI NORRIS, ANDREW W · 2009 to 2012
$1.2M
NHLBI NIH HHS HL048058NHLBI NIH HHS HL061446NHLBI NIH HHS HL062984NHLBI NIH HHS HL084207NHLBI NIH HHS P01 HL062984NHLBI NIH HHS P01 HL084207NHLBI NIH HHS R01 HL048058NHLBI NIH HHS R01 HL061446NHLBI NIH HHS R37 HL048058NIDDK NIH HHS DK081548NIDDK NIH HHS R01 DK081548
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdipokinesBiphenyl CompoundsDiabetes MellitusHumansHypoglycemic AgentsInsulin ResistanceLigandsPPAR gammaThiazolidinedionesAdipokinesBiphenyl CompoundsHypoglycemic AgentsLigandsPPAR gamma(S)-4'-((5-((1-(4-nitrophenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acidThiazolidinediones

Identifiers

PMID22223206
PMCPMC3583552

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.