ArticleJournal of computational neuroscience2012
Probabilistic modeling of selective stimulation of the human sciatic nerve with a flat interface nerve electrode.
Article in Journal of computational neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 51 citations in OpenAlex.
- A methodological framework for the efficient characterization of peripheral nerve stimulation parameters.Journal of neural engineering · 2025Trial
- The optimization of neuroprosthetic interfaces relying on biophysical and surrogate digital twins.npj biomedical innovations · 2026Review
- Automated 3D segmentation of human vagus nerve fascicles and epineurium from micro-computed tomography images using anatomy-aware neural networks.Journal of neural engineering · 2026Article
- Enhanced sensory perception and myoelectric control with high channel count implanted sensorimotor systems.Journal of neural engineering · 2025Article
- Highly efficient modeling and optimization of neural fiber responses to electrical stimulation.Nature communications · 2024Article
- AxoDetect: an automated nerve image segmentation and quantification workflow for computational nerve modeling.Journal of neural engineering · 2024Article
- Symbiotic electroneural and musculoskeletal framework to encode proprioception via neurostimulation: ProprioStim.iScience · 2023Article
- Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves.Communications biology · 2020Article
- Modelling the effects of ephaptic coupling on selectivity and response patterns during artificial stimulation of peripheral nerves.PLoS computational biology · 2020Article
- A computational model to design neural interfaces for lower-limb sensory neuroprostheses.Journal of neuroengineering and rehabilitation · 2020Article
- Automatic three-dimensional reconstruction of fascicles in peripheral nerves from histological images.PloS one · 2020Article
- Intraoperative Responses May Predict Chronic Performance of Composite Flat Interface Nerve Electrodes on Human Femoral Nerves.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2019Article
- On the parameters used in finite element modeling of compound peripheral nerves.Journal of neural engineering · 2019Article
- Influence of nerve cuff channel count and implantation site on the separability of afferent ENG.Journal of neural engineering · 2018Article
- A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve.Journal of neural engineering · 2017Article
- Quantification of human upper extremity nerves and fascicular anatomy.Muscle & nerve · 2017Article
- Neural interfaces for somatosensory feedback: bringing life to a prosthesis.Current opinion in neurology · 2015Review
- Stability and selectivity of a chronic, multi-contact cuff electrode for sensory stimulation in human amputees.Journal of neural engineering · 2015Article
- A neural interface provides long-term stable natural touch perception.Science translational medicine · 2014Article
- Selective activation of the human tibial and common peroneal nerves with a flat interface nerve electrode.Journal of neural engineering · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Ankle control is critical to both standing balance and efficient walking. The hypothesis presented in this paper is that a Flat Interface Nerve Electrode (FINE) placed around the sciatic nerve with a fixed number of contacts at predetermined locations and without a priori knowledge of the nerve's underlying neuroanatomy can selectively control each ankle motion. Models of the human sciatic nerve surrounded by a FINE of varying size were created and used to calculate the probability of selective activation of axons within any arbitrarily designated, contiguous group of fascicles. Simulations support the hypothesis and suggest that currently available implantable technology cannot selectively recruit each target plantar flexor individually but can restore plantar flexion or dorsiflexion from a site on the sciatic nerve without spillover to antagonists. Successful activation of individual ankle muscles in 90% of the population can be achieved by utilizing bipolar stimulation and/or by using a cuff with at least 20 contacts.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.