ArticleThe American journal of cardiology2012
Relations between QRS|T angle, cardiac risk factors, and mortality in the third National Health and Nutrition Examination Survey (NHANES III).
Article in The American journal of cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spatial/Frontal QRS-T Angle Predicts All-Cause Mortality and Cardiac Mortality: A Meta-Analysis.PloS one · 2015Pooled it
- Comprehensive T wave morphology assessment in a randomized clinical study of dofetilide, quinidine, ranolazine, and verapamil.Journal of the American Heart Association · 2015Trial
- Determinants of developing widened spatial QRS-T angle in HIV-infected individuals: results from the Strategies for Management of Antiretroviral Therapy [SMART] Study.Journal of electrocardiologyTrial
- Diabetes-Related Alterations in Vectorcardiographic Repolarization Geometry: Insights from Physiological and Machine-Learning Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- A new electrocardiographic evaluation in hyperkalemia: frontal QRS-T angle.Irish journal of medical science · 2025Article
- Electrocardiographic Frontal QRS-T Angle Is Independently Associated with the Presence of Celiac Disease and Disease Duration.Diagnostics (Basel, Switzerland) · 2025Article
- A Novel Electrocardiographic Marker to Predict the Development of Preeclampsia: Frontal QRS-T Angle-A Prospective Pilot Study.Medicina (Kaunas, Lithuania) · 2024Article
- The Relationship between Frontal QRS-T Angle and Vitamin D Deficiency.Medicina (Kaunas, Lithuania) · 2024Article
- Comparison of frontal QRS-T angle of patients with nasal septal deviation with healthy controls.BMC cardiovascular disorders · 2023Article
- Effect of Smokeless Tobacco (Maras Powder) on the Epicardial Fat Thickness and Ventricular Repolarization Parameters.Medicina (Kaunas, Lithuania) · 2023Article
- Comparison of Frontal QRS-T Angle in Patients with Panic Disorder and Healthy Control Group: A Preliminary Study.Psychiatry and clinical psychopharmacology · 2023Article
- The Relationship Between In-Hospital Mortality and Frontal QRS-T Angle in Patients With COVID-19.Cureus · 2022Article
- The Relationship between Insulin Resistance and Spatial QRS-T Angle in American Adults.Acta Cardiologica Sinica · 2021Article
- Decompressive Craniectomy Improves QTc Interval in Traumatic Brain Injury Patients.International journal of environmental research and public health · 2020Article
- Wide QRS-T angles are associated with markers of increased inflammatory activity independently of hypertension and diabetes.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020Article
- The association of metabolic syndrome and QRS|T angle in US adults (NHANES III).Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020Article
- Neutrophil-Lymphocyte Ratio (NLR) Reflects Myocardial Inhomogeneities in Hemodialyzed Patients.Mediators of inflammation · 2020Article
- Sleep-disordered breathing and electrocardiographic QRS-T angle: The MESA study.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Article
- Temporal changes in electrocardiographic frontal QRS-T angle and survival in patients with heart failure.PloS one · 2018Article
- Frontal QRS-T Angle and the Risk of Atrial Fibrillation in the Elderly.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
On the surface electrocardiogram, an abnormally wide QRS|T angle reflects changes in the regional action potential duration profiles and in the direction of the repolarization sequence, which is thought to increase the risk of ventricular arrhythmia. We investigated the relation between an abnormal QRS|T angle and mortality in a nationally representative sample of subjects without clinically evident heart disease. We studied 7,052 participants ≥40 years old in the third National Health and Nutrition Examination Survey with 12-lead electrocardiograms. Those with self-reported or electrocardiographic evidence of a previous myocardial infarction, QRS duration of ≥120 ms, or history of heart failure were excluded. Borderline and abnormal spatial QRS|T angles were defined according to gender-specific 75th and 95th percentiles of frequency distributions. All-cause (1,093 women and 1,191 men) and cardiovascular (462 women and 455 men) mortality during the 14-year period was assessed through linkage with the National Death Index. On multivariate analyses, an abnormal spatial QRS|T angle was associated with an increased hazard ratio (HR) for cardiovascular mortality in women (HR 1.82, 95% confidence interval 1.05 to 3.14) and men (HR 2.21, 95% confidence interval 1.32 to 3.68). Also, the multivariate adjusted HR for all-cause mortality associated with an abnormal QRS|T angle was 1.30 (95% confidence interval 0.95 to 1.78) for women and 1.87 (95% confidence interval 1.29 to 2.7) for men. A borderline QRS|T angle was not associated with an increased risk of all-cause or cardiovascular mortality. In conclusion, an abnormal QRS|T angle, as measured on a 12-lead electrocardiogram, was associated with an increased risk of cardiovascular and all-cause mortality in this population-based sample without known heart disease.
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