ArticleStem cells international2012
The potential of stem cells in the treatment of skeletal muscle injury and disease.
Article in Stem cells international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03067831 (Safety and Efficacy of Purified Autologous Bone Marrow-Derived Stem Cell Therapy for Patients With Duchenne Muscular Dystrophy.), which is not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Purified Autologous Bone Marrow-Derived Stem Cell Therapy for Patients With Duchenne Muscular Dystrophy.
Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Stem cells prevent long-term deterioration of renal function after renal artery revascularization in a renovascular hypertension model in rats.Scientific reports · 2025Article
- Sexual dimorphisms in skeletal muscle: current concepts and research horizons.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Review
- Bioprinted Notch ligand to function as stem cell niche improves muscle regeneration in dystrophic muscle.International journal of bioprinting · 2023Article
- The regenerative potential of Pax3/Pax7 on skeletal muscle injury.Journal, genetic engineering & biotechnology · 2022Review
- The effect of hypoxia on myogenic differentiation and multipotency of the skeletal muscle-derived stem cells in mice.Stem cell research & therapy · 2022Article
- Muscle Injury: Pathophysiology, Diagnosis, and Treatment.Revista brasileira de ortopedia · 2022Article
- Randomised clinical trial: Effect of administering platelet-rich fibrin to autologous fat tissue in injection laryngoplasty for vocal cord paralysis.Annals of medicine and surgery (2012) · 2021Article
- Muscle stem cells: what's new in orthopedics?Acta bio-medica : Atenei Parmensis · 2019Review
- Cellular Therapy for Chronic Traumatic Brachial Plexus Injury.Advanced biomedical research · 2018Article
- Transplanted Endothelial Progenitor Cells Improve Ischemia Muscle Regeneration in Mice by Diffusion Tensor MR Imaging.Stem cells international · 2016Article
- Duchenne muscular dystrophy: current cell therapies.Therapeutic advances in neurological disorders · 2015Review
- Biophysical cues enhance myogenesis of human adipose derived stem/stromal cells.Biochemical and biophysical research communications · 2013Article
- Mesenchymal stem cells (MSC) prevented the progression of renovascular hypertension, improved renal function and architecture.PloS one · 2013Article
- Skeletal muscle regeneration on protein-grafted and microchannel-patterned scaffold for hypopharyngeal tissue engineering.BioMed research international · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective benefit to patients with muscle disease/damage. This could include damage to muscle from trauma and include genetic abnormalities, for example, muscular dystrophies. Much of this research thus far has been focused on satellite cells, however, mesenchymal stem cells have more recently come to the fore. In particular, results of trials and further research into their use in heart failure, stress incontinence, and muscular dystrophies are eagerly awaited. Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.