Evidence map›Paper›PMID 22219695›Full record

ReviewSensors (Basel, Switzerland)2010

Recent applications of fluorescence recovery after photobleaching (FRAP) to membrane bio-macromolecules.

Gamal Rayan, Jean-Erik Guet, Nicolas Taulier, Frederic Pincet, Wladimir Urbach

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Complex Diffusion in Bacteria.Advances in experimental medicine and biology · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Phosphatidylserine dynamics in cellular membranes.Molecular biology of the cell · 2012
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gamal RayanLaboratoire de Physique Statistique de l'Ecole Normale Supérieure, associe aux Universites Paris 6 et Paris 7, CNRS UMR 8550, 24 rue Lhomond, 75005 Paris, France. gamal.rayan@lps.ens.fr
Jean-Erik Guet
Nicolas Taulier
Frederic Pincet
Wladimir Urbach

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review examines some recent applications of fluorescence recovery after photobleaching (FRAP) to biopolymers, while mainly focusing on membrane protein studies. Initially, we discuss the lateral diffusion of membrane proteins, as measured by FRAP. Then, we talk about the use of FRAP to probe interactions between membrane proteins by obtaining fundamental information such as geometry and stoichiometry of the interacting complex. Afterwards, we discuss some applications of FRAP at the cellular level as well as the level of organisms. We conclude by comparing diffusion coefficients obtained by FRAP and several other alternative methods.

Indexed as

AnimalsFluorescence Recovery After PhotobleachingHumansMacromolecular SubstancesMembrane ProteinsMembranesModels, BiologicalModels, TheoreticalMacromolecular SubstancesMembrane Proteinsbiomembranesbiomolecular interactionsdiffusionFluorescence Recovery after Photobleaching (FRAP)

Identifiers

PMID22219695
PMCPMC3247740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.