ReviewJournal of biomedicine & biotechnology2011
Modulation of specific and allergy-related immune responses by helminths.
Review in Journal of biomedicine & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 59 citations in OpenAlex.
- Levels of Exhaled Fraction of Nitric Oxide (FeNO) and Type 2 Biomarkers in Individuals Naturally Exposed to Helminth Parasites in a Tropical Region.International journal of molecular sciences · 2025Article
- Article
- Measuring the Manipulation of T Helper Immune Responses byInternational journal of molecular sciences · 2022Article
- Interleukin-35 is a critical regulator of immunity during helminth infections associated with multiple sclerosis.Immunology · 2021Article
- Concomitant experimental coinfection by Plasmodium berghei NK65-NY and Ascaris suum downregulates the Ascaris-specific immune response and potentiates Ascaris-associated lung pathology.Malaria journal · 2021Article
- House dust mite sensitization drives cross-reactive immune responses to homologous helminth proteins.PLoS pathogens · 2021Article
- Immunomodulatory effect of different extracts from Angiostrongylus cantonensis on airway inflammation in an allergic asthma model.Parasitology research · 2020Article
- Schistosomal extracellular vesicle-enclosed miRNAs modulate host T helper cell differentiation.EMBO reports · 2020Article
- What Can Parasites Tell Us About the Pathogenesis and Treatment of Asthma and Allergic Diseases.Frontiers in immunology · 2020Review
- Allergen presensitization drives an eosinophil-dependent arrest in lung-specific helminth development.The Journal of clinical investigation · 2019Article
- Helminth parasites and immune regulation.F1000Research · 2018Review
- Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes.PLoS neglected tropical diseases · 2017Article
- Identification of three immunodominant motifs with atypical isotype profile scattered over the Onchocerca volvulus proteome.PLoS neglected tropical diseases · 2017Article
- Community deworming alleviates geohelminth-induced immune hyporesponsiveness.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Parasitic infection as a potential therapeutic tool against rheumatoid arthritis.Experimental and therapeutic medicine · 2016Article
- Regulation of the host immune system by helminth parasites.The Journal of allergy and clinical immunology · 2016Review
- Testing small molecule analogues of the Acanthocheilonema viteae immunomodulator ES-62 against clinically relevant allergens.Parasite immunology · 2016Article
- Diplomatic Assistance: Can Helminth-Modulated Macrophages Act as Treatment for Inflammatory Disease?PLoS pathogens · 2016Review
- Schistosome-Derived Molecules as Modulating Actors of the Immune System and Promising Candidates to Treat Autoimmune and Inflammatory Diseases.Journal of immunology research · 2016Review
- The Helminth-Derived Immunomodulator AvCystatin Reduces Virus Enhanced Inflammation by Induction of Regulatory IL-10+ T Cells.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helminths are master regulators of host immune responses utilising complex mechanisms to dampen host protective Th2-type responses and favour long-term persistence. Such evasion mechanisms ensure mutual survival of both the parasite and the host. In this paper, we present recent findings on the cells that are targeted by helminths and the molecules and mechanisms that are induced during infection. We discuss the impact of these factors on the host response as well as their effect in preventing the development of aberrant allergic inflammation. We also examine recent findings on helminth-derived molecules that can be used as tools to pinpoint the underlying mechanisms of immune regulation or to determine new anti-inflammatory therapeutics.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.