ArticleMolecular vision2011
An association study of the COL1A1 gene and high myopia in a Han Chinese population.
Article in Molecular vision, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Polymorphism in the RASGRF1 gene with high myopia: A meta-analysis.Molecular vision · 2015Pooled it
- Decreased Levels of DNA Methylation in the PCDHA Gene Cluster as a Risk Factor for Early-Onset High Myopia in Young Children.Investigative ophthalmology & visual science · 2022Article
- Insight into the molecular genetics of myopia.Molecular vision · 2017Review
- Genetic association of COL1A1 polymorphisms with high myopia in Asian population: a Meta-analysis.International journal of ophthalmology · 2016Article
- Association of COL1A1 polymorphism with high myopia: a Meta-analysis.International journal of ophthalmology · 2016Article
- Evaluation of 10 AMD Associated Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes.PloS one · 2016Article
- The genetic mechanisms of primary angle closure glaucoma.Eye (London, England) · 2015Review
- Association between COL1A1 polymorphisms and high myopia: a meta-analysis.International journal of clinical and experimental medicine · 2015Article
- Article
- The +1245g/t polymorphisms in the collagen type I alpha 1 (col1a1) gene in polish skiers with anterior cruciate ligament injury.Biology of sport · 2013Article
- Is Hyperopia an Important Risk Factor for PACG in the Dutch Population?-A Case Control Study.Journal of ophthalmology · 2013Article
- Article
- Genetic Basis of Primary Angle Closure Glaucoma: The Role of Collagens and Extracellular Matrix.Journal of ophthalmic & vision researchArticle
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSingle nucleotide polymorphisms (SNPs) in the collagen type I (COL1A1) gene have been shown to be significantly associated with high myopia in a Japanese population. This present study was conducted to investigate whether COL1A1 is associated with high myopia in a Han Chinese population.
methodsHigh myopia is defined by a spherical equivalent of less than or equal to -6.00 diopter sphere and an axial length longer than or equal to 26.0 mm in the affected eye. We genotyped rs2075555 and rs2269336 SNPs in COL1A1 in a Ha n Chinese group composed of 697 high myopia patients and 762 normal controls.
resultsNeither of the two SNPs showed significant association with high myopia (p(allelic)=0.252 for rs2075555, and p(allelic)=0.699 for rs2269336).
conclusionsOur study revealed that SNPs in COL1A1 are not significantly associated with high myopia in the Han Chinese population.
Indexed as
Identifiers
22219633PMC3247168W2125093868What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.