Evidence map›Paper›PMID 22219587›Full record

ArticleJournal of pharmacy & bioallied sciences2011

Antibiotic prescription patterns at admission into a tertiary level intensive care unit in Northern India.

Aparna Williams, Ashu S Mathai, Atul S Phillips

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  6. Study of Antimicrobial Utilization and Cost of Therapy in Medicine Intensive Care Unit of a Tertiary Care Hospital in Eastern India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
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  11. Review
  12. Observational
  13. Article
  14. Antimicrobial agents' utilization and cost pattern in an Intensive Care Unit of a Teaching Hospital in South India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016
    Article
  15. Removal rates of antibiotics in four sewage treatment plants in South India.Environmental science and pollution research international · 2016
    Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aparna WilliamsDepartments of Anesthesiology and Critical Care, Christian Medical College, Ludhiana, Punjab, India.
Ashu S Mathai
Atul S Phillips

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAn audit of antibiotic prescribing patterns is an important indicator of the quality and standard of clinical practice.

aimsTo study the (1) antibiotic prescription and consumption patterns at admission into the intensive care unit (ICU); (2) average costs of antibiotics prescribed; and (3) correlation of antibiotic usage and the costs incurred with age, severity of illness, and diagnosis. SETTINGS AND

designA 13-bedded tertiary level ICU. A prospective, observational audit. MATERIALS AND

methodsTwo hundred consecutive prescriptions on patients admitted to the ICU from August to October, 2008, were audited. The total number of drugs and antibiotics, the class, dose, route, and cost of antibiotics were noted and the Defined Daily Dose/100 bed-days (DDD/100 bed-days) of the 10 most frequently prescribed antibiotics were calculated. STATISTICAL ANALYSIS USED: Univariate analysis was performed using Epi Info software (version 8.0).

resultsA total of 1246 drugs and 418 antibiotics were prescribed in the 200 patients studied, that is, an average of 6.23 (± SD 2.73) drugs/prescription and 2.09 (± SD 1.27) antibiotics/prescription. Antibiotics were prescribed on 190 patients (95%) at admission. There was a significant correlation between the number of patients prescribed three or more antibiotics and mortality rates (53% nonsurvivors vs. 33.5% survivors (P = 0.015). The average cost of the antibiotics was Rupees 1995.08 (± SD 2099.99) per patient and antibiotics expenditure accounted for 73.2% of the total drug costs.

conclusionsAntibiotics are commonly prescribed to most ICU patients at admission and contribute significantly to the total drug costs. Antibiotic restriction policies and a multidisciplinary effort to reduce usage are urgently required.

Indexed as

Admissionantibiotic usageintensive care unitprescriptions

Identifiers

PMID22219587
PMCPMC3249701

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.