Evidence map›Paper›PMID 22219508›Full record

ReviewGenetics2012

Morphogenesis and the cell cycle.

Audrey S Howell, Daniel J Lew

Open access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 153 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The Role of the Cell Integrity Pathway in Septum Assembly in Yeast.Journal of fungi (Basel, Switzerland) · 2021
    Review
  19. Article
  20. In Vitro Apoptotic Cell Death Assessment.Methods in molecular biology (Clifton, N.J.) · 2021
    Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Audrey S HowellDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Daniel J Lew
Duke Medical Center · USDuke University Hospital · US

Funding

POLARITY ESTABLISHMENT IN YEASTR01GM062300 · NIGMS · DUKE UNIVERSITY · PI LEW, DANIEL J · 2001 to 2016
$5.0M
CELL CYCLE CHECKPOINT THAT MONITORS MORPHOGENESISR01GM053050 · NIGMS · DUKE UNIVERSITY · PI LEW, DANIEL J · 1995 to 2012
$4.0M
NIGMS NIH HHS GM53050NIGMS NIH HHS GM62300NIGMS NIH HHS R01 GM053050NIGMS NIH HHS R01 GM062300
6 · The paper itself

Abstract

Studies of the processes leading to the construction of a bud and its separation from the mother cell in Saccharomyces cerevisiae have provided foundational paradigms for the mechanisms of polarity establishment, cytoskeletal organization, and cytokinesis. Here we review our current understanding of how these morphogenetic events occur and how they are controlled by the cell-cycle-regulatory cyclin-CDK system. In addition, defects in morphogenesis provide signals that feed back on the cyclin-CDK system, and we review what is known regarding regulation of cell-cycle progression in response to such defects, primarily acting through the kinase Swe1p. The bidirectional communication between morphogenesis and the cell cycle is crucial for successful proliferation, and its study has illuminated many elegant and often unexpected regulatory mechanisms. Despite considerable progress, however, many of the most puzzling mysteries in this field remain to be resolved.

Indexed as

CDC28 Protein Kinase, S cerevisiaeCell CycleCytokinesisMorphogenesisQuorum SensingSaccharomyces cerevisiaeCDC28 Protein Kinase, S cerevisiae

Identifiers

PMID22219508
PMCPMC3249366
OpenAlexW2159958620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.