ArticleJournal of neurophysiology2012
Sound sensitivity of neurons in rat hippocampus during performance of a sound-guided task.
Article in Journal of neurophysiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Exposure to broadband noise during non-REM sleep impairs hippocampal sharp-wave ripples and memory consolidation.Current biology : CB · 2026Article
- Neuronal mismatch responses to auditory stimuli in the dorsal hippocampus of anesthetized rats.Communications biology · 2025Article
- The medial entorhinal cortex encodes multisensory spatial information.Cell reports · 2024Article
- Distal but not local auditory information supports spatial representations by place cells.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- The meso-connectomes of mouse, marmoset, and macaque: network organization and the emergence of higher cognition.Cerebral cortex (New York, N.Y. : 1991) · 2024Review
- Hippocampal cognitive and relational map paradigms explored by multisensory encoding recording with wide-field calcium imaging.iScience · 2024Article
- The hearing hippocampus.Progress in neurobiology · 2022Review
- Natural acoustic stimuli evoke selective responses in the hippocampus of passive listening bats.Hippocampus · 2022Article
- Review
- Moving bar of light evokes vectorial spatial selectivity in the immobile rat hippocampus.Nature · 2022Article
- Sensitivity of neural responses in the inferior colliculus to statistical features of sound textures.Hearing research · 2021Article
- Do hippocampal pyramidal cells respond to nonspatial stimuli?Physiological reviews · 2021Review
- Temporary conductive hearing loss in early life impairs spatial memory of rats in adulthood.Brain and behavior · 2018Article
- NMDA receptor-gated visual responses in hippocampal CA1 neurons.The Journal of physiology · 2018Article
- Septal and Hippocampal Neurons Contribute to Auditory Relay and Fear Conditioning.Frontiers in cellular neuroscience · 2018Article
- The Cortical States of Wakefulness.Frontiers in systems neuroscience · 2018Review
- Prefrontal-hippocampal interactions in episodic memory.Nature reviews. Neuroscience · 2017Review
- Balanced Noise-Evoked Excitation and Inhibition in Awake Mice CA3.Frontiers in physiology · 2017Article
- Neural Representation. A Survey-Based Analysis of the Notion.Frontiers in psychology · 2017Article
- Still searching for the engram.Learning & behavior · 2016Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate how hippocampal neurons encode sound stimuli, and the conjunction of sound stimuli with the animal's position in space, we recorded from neurons in the CA1 region of hippocampus in rats while they performed a sound discrimination task. Four different sounds were used, two associated with water reward on the right side of the animal and the other two with water reward on the left side. This allowed us to separate neuronal activity related to sound identity from activity related to response direction. To test the effect of spatial context on sound coding, we trained rats to carry out the task on two identical testing platforms at different locations in the same room. Twenty-one percent of the recorded neurons exhibited sensitivity to sound identity, as quantified by the difference in firing rate for the two sounds associated with the same response direction. Sensitivity to sound identity was often observed on only one of the two testing platforms, indicating an effect of spatial context on sensory responses. Forty-three percent of the neurons were sensitive to response direction, and the probability that any one neuron was sensitive to response direction was statistically independent from its sensitivity to sound identity. There was no significant coding for sound identity when the rats heard the same sounds outside the behavioral task. These results suggest that CA1 neurons encode sound stimuli, but only when those sounds are associated with actions.
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