ArticleParasitology research2012
Anti-Trichomonas vaginalis activity of saponins from Quillaja, Passiflora, and Ilex species.
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
12 citing papers in PubMed, 36 citations in OpenAlex.
- The effects of graded levels of quillaja saponins on the productivity of commercial laying hens.Poultry science · 2026Article
- Anti-trichomonad activities of different compounds from foods, marine products, and medicinal plants: a review.BMC complementary medicine and therapies · 2020Review
- Saponins fromMolecules (Basel, Switzerland) · 2019Review
- Anti-Trichomonas vaginalis activity of ursolic acid derivative: a promising alternative.Parasitology research · 2018Article
- Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula.PloS one · 2017Article
- In vitro anti-Trichomonas vaginalis activity of Pistacia lentiscus mastic and Ocimum basilicum essential oil.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2015Article
- Natural and synthetic compound anti-Trichomonas vaginalis: an update review.Parasitology research · 2015Review
- Anti-Trichomonas vaginalis activity from triterpenoid derivatives.Parasitology research · 2014Article
- The effect of 3-(biphenyl-4-yl)-3-hydoxyquinuclidine (BPQ-OH) and metronidazole on Trichomonas vaginalis: a comparative study.Parasitology research · 2014Article
- Spermicidal and anti-Trichomonas vaginalis activity of Brazilian Sapindus saponaria.BMC complementary and alternative medicine · 2013Article
- Tannins possessing bacteriostatic effect impair Pseudomonas aeruginosa adhesion and biofilm formation.PloS one · 2013Article
- Remarkable anti-trichomonas vaginalis activity of plants traditionally used by the Mbyá-Guarani indigenous group in Brazil.BioMed research international · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trichomonas vaginalis is a flagellated protozoan that causes trichomonosis, the most prevalent non-viral STD worldwide. The pathogen has been associated with serious health consequences including predisposition to cervical cancer and adverse pregnancy outcomes and infertility. It also acts as a co-factor in HIV transmission and acquisition. The 5-nitroimidazole drugs are used in the treatment, however, treatment noncompliance is observed, and a growing number of T. vaginalis isolates resistant to the drugs have been related. Saponins are natural products possessing many biological activities such as antiprotozoan activity. The aim of this study was to evaluate the anti-T. vaginalis activity of saponins from Quillaja, Passiflora, and Ilex species. Saponins from Passiflora alata and Quillaja saponaria presented the best anti-T. vaginalis activity (MIC = 0.025%). In addition, all samples induced erythrocyte lysis and LDH release. As far as we know, this is the first report demonstrating the potential anti-T. vaginalis activity of these saponins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.