ArticleApplied microbiology and biotechnology2012
Expanding the set of rhodococcal Baeyer-Villiger monooxygenases by high-throughput cloning, expression and substrate screening.
Article in Applied microbiology and biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 73 citations in OpenAlex.
- The Flexible Peripheral Segments Modulate the Catalytic Activity of the FAD-Containing Monooxygenase EthA fromBiomolecules · 2026Article
- Surveying aIranian journal of microbiology · 2026Article
- Characterization of C16-C36 alkane degradation and oily sludge bioremediation byApplied and environmental microbiology · 2025Article
- Recombinant Expression and Characterization of a Novel Type I Baeyer-Villiger Monooxygenase from aInternational journal of molecular sciences · 2025Article
- Optimization of growth and induction conditions for the production of recombinant whole cell cyclohexanone monooxygenase in Escherichia coli.Scientific reports · 2025Article
- Immobilization of Baeyer-Villiger monooxygenase from acetone grown Fusarium sp.Biotechnology letters · 2022Article
- A Baeyer-Villiger monooxygenase from Cupriavidus basilensis catalyzes asymmetric synthesis of (R)-lansoprazole and other pharmaco-sulfoxides.Applied microbiology and biotechnology · 2021Article
- Enantioselective sulfoxidation usingRSC advances · 2020Article
- The Phylogeny of Class B Flavoprotein Monooxygenases and the Origin of the YUCCA Protein Family.Plants (Basel, Switzerland) · 2020Article
- Review
- Efficient Synthesis of Methyl 3-Acetoxypropionate by a Newly Identified Baeyer-Villiger Monooxygenase.Applied and environmental microbiology · 2019Article
- Editorial:Frontiers in microbiology · 2019Article
- Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme.ACS catalysis · 2018Article
- Article
- Application of a thermostable Baeyer-Villiger monooxygenase for the synthesis of branched polyester precursors.Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) · 2018Article
- Comparative Transcriptome Analysis Reveals the Mechanism Underlying 3,5-Dibromo-4-Hydroxybenzoate Catabolism via a New Oxidative Decarboxylation Pathway.Applied and environmental microbiology · 2018Article
- Mining the Genome ofFrontiers in microbiology · 2018Article
- Cloning and characterization of the Type I Baeyer-Villiger monooxygenase from Leptospira biflexa.AMB Express · 2017Article
- Prospecting Biotechnologically-Relevant Monooxygenases from Cold Sediment Metagenomes: An In Silico Approach.Marine drugs · 2017Article
- Chopping and Changing: the Evolution of the Flavin-dependent Monooxygenases.Journal of molecular biology · 2016Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To expand the available set of Baeyer-Villiger monooxygenases (BVMOs), we have created expression constructs for producing 22 Type I BVMOs that are present in the genome of Rhodococcus jostii RHA1. Each BVMO has been probed with a large panel of potential substrates. Except for testing their substrate acceptance, also the enantioselectivity of some selected BVMOs was studied. The results provide insight into the biocatalytic potential of this collection of BVMOs and expand the biocatalytic repertoire known for BVMOs. This study also sheds light on the catalytic capacity of this large set of BVMOs that is present in this specific actinomycete. Furthermore, a comparative sequence analysis revealed a new BVMO-typifying sequence motif. This motif represents a useful tool for effective future genome mining efforts.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.