ArticleCognitive, affective & behavioral neuroscience2012
Affective regulation of cognitive-control adjustments in remitted depressive patients after acute tryptophan depletion.
Article in Cognitive, affective & behavioral neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 38 citations in OpenAlex.
- Mood states influence cognitive control: the case of conflict adaptation.Psychological research · 2015Trial
- Lifetime Trauma History and Cognitive Functioning in Major Depression and Their Role for Cognitive-Behavioral Therapy Outcome.Clinical psychology in Europe · 2021Article
- Mood state and conflict adaptation: an update and a diffusion model analysis.Psychological research · 2021Article
- Conflict monitoring and the affective-signaling hypothesis-An integrative review.Psychonomic bulletin & review · 2020Review
- Does conflict help or hurt cognitive control? Initial evidence for an inverted U-shape relationship between perceived task difficulty and conflict adaptation.Frontiers in psychology · 2015Article
- Trauma exposure is associated with increased context-dependent adjustments of cognitive control in patients with posttraumatic stress disorder and healthy controls.Cognitive, affective & behavioral neuroscience · 2014Article
- The influence of approach-avoidance motivational orientation on conflict adaptation.Cognitive, affective & behavioral neuroscience · 2014Article
- Conflict adaptation is predicted by the cognitive, but not the affective alexithymia dimension.Frontiers in psychology · 2014Article
- Common mechanisms of pain and depression: are antidepressants also analgesics?Frontiers in behavioral neuroscience · 2014Article
- Pupil dilation in the Simon task as a marker of conflict processing.Frontiers in human neuroscience · 2013Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Negative affect in healthy populations regulates the appraisal of demanding situations, which tunes subsequent effort mobilization and adjustments in cognitive control. In the present study, we hypothesized that dysphoria in depressed individuals similarly modulates this adaptation, possibly through a neural mechanism involving serotonergic regulation. We tested the effect of dysphoria induced by acute tryptophan depletion (ATD) in remitted depressed patients on conflict adaptation in a Simon task. ATD temporarily lowers the availability of the serotonin precursor L-Tryptophan and is known to increase depressive symptoms in approximately half of remitted depressed participants. We found that depressive symptoms induced by ATD were associated with increased conflict adaptation. Our finding extends recent observations implying an important role of affect in regulating conflict-driven cognitive control.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.