Evidence map›Paper›PMID 22218743›Full record

ReviewSleep & breathing = Schlaf & Atmung2012

The actual role of sodium cromoglycate in the treatment of asthma--a critical review.

Nikolaus C Netzer, T Küpper, Hans W Voss, Arn H Eliasson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sleep & breathing = Schlaf & Atmung, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 36 citations in OpenAlex.

  1. Dissecting SNARE-Mediated Exocytosis in RBL-2H3 Mast Cells.Methods in molecular biology (Clifton, N.J.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Nikolaus C NetzerHermann Buhl Institute for Hypoxia and Sleep Medicine Research, Paracelsus Medical University, Salzburg, Austria. nikinetzer@yahoo.com
T Küpper
Hans W Voss
Arn H Eliasson
Hermann Buhl Institut · DERWTH Aachen University · DEUniformed Services University of the Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite international consensus and clearly written guidelines urging wider use of corticosteroids or combinations of inhaled short- and long-acting β-agonists (SABA and LABA) and corticosteroids in persistent asthma, prescribing patterns and compliance rates fall far short of recommendations.

objectivesThe failure to use steroids more aggressively is due, in part, to their side effects, even with inhaled forms of the drug. There is a role for expanded use of sodium cromolyn in asthma. Its potent anti-inflammatory effects, lack of side effects, and acceptable dosing and method of delivery, as well as its special role in exercise-induced asthma, make it a very suitable choice in the initial therapy for control of asthma.

conclusionCompared to SABA and LABA, cromoglycates alone are unsuspicious of being used to enhance physical performance.

Indexed as

Adrenergic beta-2 Receptor AgonistsAdultAnti-Asthmatic AgentsAsthmaAsthma, Exercise-InducedBody HeightChildCromolyn SodiumDelayed-Action PreparationsDose-Response Relationship, DrugDrug Therapy, CombinationHumansLong-Term CareMedication AdherenceSympathomimeticsAdrenergic beta-2 Receptor AgonistsAnti-Asthmatic AgentsCromolyn SodiumDelayed-Action PreparationsSympathomimetics

Identifiers

PMID22218743
OpenAlexW2070909139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.