Evidence map›Paper›PMID 22218641›Full record

ArticleRheumatology international2013

Home-based exercise therapy in ankylosing spondylitis: short-term prospective study in patients receiving tumor necrosis factor alpha inhibitors.

Semra Yigit, Zerrin Sahin, Saliha Eroglu Demir, Deniz Hatun Aytac

Registry-linked trialAbstract read
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In one paragraph

Article in Rheumatology international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01690273 (Effect of Two Exercise Therapy Program With and Without Elastic Resistance in Ankylosing Spondylitis Patients), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01690273 nacompletednot on this map

Effect of Two Exercise Therapy Program With and Without Elastic Resistance in Ankylosing Spondylitis Patients

TypeinterventionalSponsorUniversity of Sao PauloRan2012 to 2014Enrolled55ConditionsAnkylosing SpondylitisArmsmobility exercise, mobility and elastic resistance exercise
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. The health-related quality of life of ankylosing spondylitis patients assessed by SF-36: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016
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  14. Observational
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  18. The impact of ankylosing spondylitis on female sexual functions.International journal of impotence research · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Semra YigitMinistry of Health, Gebze Fatih State Hospital, Physical Medicine and Rehabilitation Clinic, Izmit, Turkey.
Zerrin Sahin
Saliha Eroglu Demir
Deniz Hatun Aytac

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of exercise and regular physiotherapy in patients with ankylosing spondylitis (AS) under treatment with tumor necrosis factor alpha inhibitors (TNFα inhibitors) was reported in some studies, but the literature on this topic is still scarce. The aim of this study was to assess the effects of home-based exercise therapy on functional capacity, disease activity, spinal mobility, quality of life, emotional state and fatigue in patients with AS receiving TNFα inhibitors. Forty-two AS patients were trained on the disease, and home-based exercise program was demonstrated to all the patients. At baseline and at the end of 10 week, we evaluated Bath AS Disease Activity Index, Bath AS Functional Index, Bath AS Metrology Index, Multidimensional Assessment of Fatigue Scale, Beck Depression Inventory and Short-Form 36. Patients following home-based exercise program five times a week at least 30 min per session (exercise group) were compared with those exercising less than five times a week (control group). At baseline, exercise and control group had similar demographic features. After 10 weeks, all outcome parameters showed statistically significant improvements in exercise group. There were significant differences in all the parameters except social functioning subscale of Short-Form 36 between groups in favor of exercise group at 10th week (P < 0.05). Home-based exercise program is an effective therapy in increasing functional capacity and joint mobility, decreasing disease activity, improving emotional state, fatigue and quality of life for AS patient receiving TNFα inhibitors. We need to find out new ways to provide continuity of AS patients with it.

Indexed as

Exercise TherapySelf CareAdolescentAdultAgedAntibodies, MonoclonalAntirheumatic AgentsCombined Modality TherapyDepressionFatigueFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeAntibodies, MonoclonalAntirheumatic AgentsTumor Necrosis Factor-alpha

Identifiers

PMID22218641

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.