Evidence map›Paper›PMID 22218407›Full record

ArticleLab on a chip2012

Antigen-responsive, microfluidic valves for single use diagnostics.

Brad J Berron, Allison M May, Zheng Zheng, Vivek Balasubramaniam, Christopher N Bowman

Abstract read
In one paragraph

Article in Lab on a chip, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Increased yield of gelatin coated therapeutic cells through cholesterol insertion.Journal of biomedical materials research. Part A · 2021
    Article
  2. Article
  3. Article
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brad J BerronChemical and Biological Engineering, UCB 424, University of Colorado, Boulder, CO 80309, USA.
Allison M May
Zheng Zheng
Vivek Balasubramaniam
Christopher N Bowman

Funding

ACADEMIC TRAINING PROGRAM IN PEDIATRIC PULMONARY DISEASET32HL007670 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ABMAN, STEVEN HERBERT · 1988 to 2019
$5.9M
Collaboration in the Development of Novel Polymerization Enhanced ImmunofluoresceR21EB012188 · NIBIB · UNIVERSITY OF COLORADO · PI BOWMAN, CHRISTOPHER N · 2011 to 2012
$413k
High Amplification Detection of Genetic Cancer MarkersR21CA127884 · NCI · UNIVERSITY OF COLORADO · PI BOWMAN, CHRISTOPHER N · 2008 to 2009
$367k
NCI NIH HHS R21 CA 127884NCI NIH HHS R21 CA127884NHLBI NIH HHS 5T32 HL007670-18NHLBI NIH HHS T32 HL007670NIBIB NIH HHS R21 EB012188
6 · The paper itself

Abstract

The growing need for medical diagnostics in resource limited settings is driving the development of simple, standalone immunoassay devices. A capillary flow device using polymerization based amplification is capable of blocking a microfluidic channel in response to target biomaterials, enabling multiple modes of detection that require little or no supplemental instrumentation.

Indexed as

AntigensHumansImmunoassayMicrofluidic Analytical TechniquesAntigens

Identifiers

PMID22218407
PMCPMC4030428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.