ArticleJournal of human hypertension2013
High normal blood pressure is an independent risk factor for cardiovascular disease among middle-aged but not in elderly populations: 9-year results of a population-based study.
Article in Journal of human hypertension, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effects of Vegetarian Diets on Blood Pressure Lowering: A Systematic Review with Meta-Analysis and Trial Sequential Analysis.Nutrients · 2020Pooled it
- Prehypertension and the risk of coronary heart disease in Asian and Western populations: a meta-analysis.Journal of the American Heart Association · 2015Pooled it
- Association between pre-hypertension and cardiovascular outcomes: a systematic review and meta-analysis of prospective studies.Current hypertension reports · 2013Pooled it
- Prehypertension and incidence of cardiovascular disease: a meta-analysis.BMC medicine · 2013Pooled it
- [Impact of Anthropometric Indices of Obesity on the Risk of Incident Hypertension in Adults with Prehypertension: A Secondary Analysis of a Cohort Study].Journal of Korean Academy of Nursing · 2024Article
- Risk of Higher Blood Pressure in 3 to 6 Years Old Singleton Born From OHSS Patients Undergone With Fresh IVF/ICSI.Frontiers in endocrinology · 2022Article
- Diabetes modifies the association of prehypertension with cardiovascular disease and all-cause mortality.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- The Non-linear Relationship Between Normal Range Systolic Blood Pressure and Cardiovascular or All-Cause Mortality Among Elderly Population.Frontiers in cardiovascular medicine · 2021Article
- Article
- The association of stage 1 hypertension defined by the 2017 ACC/AHA hypertension guideline and subsequent cardiovascular events among adults <50 years.Journal of human hypertension · 2020Article
- Relationship of the Blood Pressure Categories, as Defined by the ACC/AHA 2017 Blood Pressure Guidelines, and the Risk of Development of Cardiovascular Disease in Low-Risk Young Adults: Insights From a Retrospective Cohort of Young Adults.Journal of the American Heart Association · 2019Article
- Status of Hypertension in Tehran: Potential impact of the ACC/AHA 2017 and JNC7 Guidelines, 2012-2015.Scientific reports · 2019Article
- A Stroke Risk Detection: Improving Hybrid Feature Selection Method.Journal of medical Internet research · 2019Article
- Prevalence of Self-Reported Hypertension in Deaf Adults Who Use American Sign Language.American journal of hypertension · 2018Article
- Blood Pressure and Hypertension: Findings from 20 Years of the Tehran Lipid and Glucose Study (TLGS).International journal of endocrinology and metabolism · 2018Review
- Different combinations of glucose tolerance and blood pressure status and incident cardiovascular disease and all-cause mortality events.Journal of human hypertension · 2017Article
- High-normal blood pressure is associated with new-onset electrocardiographic left ventricular hypertrophy.Journal of human hypertension · 2015Article
- Article
- Younger females are at greater risk of vasodilation-related adverse symptoms caused by dihydropyridine calcium channel blockers: results of a study of 11,918 Japanese patients.Clinical drug investigation · 2014Article
- Sex-specific blood biomarkers linked to memory changes in middle-aged adults: The Framingham Heart Study.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Data are conflicting and sparse regarding the impact of high normal blood pressure (BP) (systolic BP (SBP) of 130-139 mm Hg or diastolic BP (DBP) of 85-89 mm Hg) on incident cardiovascular disease (CVD) among middle-aged vs elderly population. We examined the risk of BP categories among 6273 participants ≥ 30 years, free of CVD at baseline, during more than 9.3 years follow-up. Cox regression analysis was used to estimate the hazard ratio (HR) of CVD for normal BP group (SBP between 120-129 mmHg or DBP between 80-85 mmHg), high normal BP group and hypertension group (SBP ≥ 140 mm Hg or DBP ≥ 90 mmHg or taking antihypertensive drugs), considering those with optimal BP (SBP<120 mmHg and DBP<80 mmHg) as reference. During follow-up, 512 CVD events occurred. There was significant interaction between age and BP categories (P=0.028) in prediction of CVD. In multivariate analysis, HRs (95% CIs) of CVD were 1.62 (1.11-2.37) and 2.20 (1.57-3.09) for middle aged with high normal and hypertensive BP groups, respectively. Among elderly (≥ 60 years), HR was 2.09 (1.36-3.21) only for hypertensive ones. High normal BP is a risk factor for incident of CVD only among middle-aged population. Furthermore, the effect of hypertension on incident CVD was stronger among younger population.
Indexed as
Identifiers
22217674What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.