ArticleHealth physics2012
Radiation dose to the fetus from [(18)F]-FDG administration during the second trimester of pregnancy.
Article in Health physics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Use of Positron Emission Tomography for Pregnancy-Associated Cancer Assessment: A Review.Journal of clinical medicine · 2022Review
- Radiation Absorbed Dose to the Embryo and Fetus from Radiopharmaceuticals.Seminars in nuclear medicine · 2022Review
- The use of PET/CT in pregnancy: A case report of malignant parathyroid carcinoma and a review of the literature.Obstetric medicine · 2018Article
- Hodgkin's Disease Staging by FDG PET/CT in a Pregnant Woman.Nuclear medicine and molecular imaging · 2014Article
- Article
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Authors and funding
4 authors.
Funding
Abstract
The authors estimated the fetal radiation dose from [(18)F]-FDG in a rare case of a woman who underwent a PET/CT scan during the second trimester of pregnancy. The patient, a 27-y-old female with a paraganglioma, received 181.3 MBq [(18)F]-FDG. From the concentrations of radioactivity measured on the images, the time-integrated activity coefficients of the fetus and the placenta were derived. The time-integrated activity coefficients of the mother's organs were taken from the standard values of ICRP publication 106. The final fetal dose was calculated using the 6-mo pregnant model of the OLINDA/EXM software. The fetus showed an overall low and homogeneous [(18)F]-FDG uptake, with an average concentration of 2.41 kBq cm(-3). The uptake in the placenta was generally higher (average concentration = 3.69 kBq cm(-3)). The estimated time-integrated activity coefficients were 0.0130 and 0.0058 Bq h Bq(-1) for the fetus and the placenta, respectively. The final average dose to the fetus was 1.97 × 10(-2) mGy MBq(-1) (3.6 mGy in this patient who received 181.3 MBq). Therefore, the dose to the fetus from [(18)F]-FDG administration during the second trimester of pregnancy is low. When medically indicated, pregnancy should not be a categorical basis for withholding [(18)F]-FDG PET scans.
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