Evidence map›Paper›PMID 22217471›Full record

ArticleThe Journal of pediatrics2012

Health-related quality of life in adolescents with or at risk for type 2 diabetes mellitus.

Erinn T Rhodes, Michael I Goran, Tracy A Lieu, Robert H Lustig, Lisa A Prosser, Thomas J Songer, Marc J Weigensberg, Ruth S Weinstock, Tessa Gonzalez, Kaitlin Rawluk and 3 more

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in The Journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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  15. Psychosocial burden and glycemic control during the first 6 years of diabetes: results from the SEARCH for Diabetes in Youth study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 1 country.

Erinn T RhodesDivision of Endocrinology, Children's Hospital Boston, Boston, MA, USA. Erinn.Rhodes@childrens.harvard.edu
Michael I Goran
Tracy A Lieu
Robert H Lustig
Lisa A Prosser
Thomas J Songer
Marc J Weigensberg
Ruth S Weinstock
Tessa Gonzalez
Kaitlin Rawluk
Roula M Zoghbi
David S Ludwig
Lori M Laffel
Harvard Pilgrim Health Care · USUniversity of Southern California · USBoston Children's Hospital · USDuke University · USHarvard University · USJoslin Diabetes Center · USPalmetto Health Richland · USSUNY Upstate Medical University · USTexas Children's Hospital · USUniversity of California, San Francisco · USUniversity of Pittsburgh · US

Funding

Effects of Diet on Hormones, Metabolism and Body WeightK24DK082730 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LUDWIG, DAVID S · 2009 to 2018
$1.6M
Health Values and Treatment of Pediatric Type 2 DiabetesK01DP000089 · DP · CHILDREN'S HOSPITAL BOSTON · PI RHODES, ERINN · 2004 to 2006
$210k
NCCDPHP CDC HHS K01 DP000089NCCDPHP CDC HHS K01DP000089NIDDK NIH HHS K24 DK082730NIDDK NIH HHS K24DK082730
6 · The paper itself

Abstract

objectiveTo evaluate how adolescents with or at risk for type 2 diabetes mellitus (T2DM) and their parent/guardians (parents) perceive adolescents' health-related quality of life. STUDY

designWe interviewed overweight/obese, 12- to 18-year-old youth with T2DM, prediabetes, or insulin resistance and one parent from 5 US sites. Assessments included Pediatric Quality of Life Inventory (PedsQL), Health Utilities Index, family conflict, and diabetes burden.

resultsIn 108 adolescents, diagnoses included 40.7% with T2DM, 25.0% with prediabetes, and 34.3% with insulin resistance. PedsQL summary score (SS) was higher in adolescents than parents (P=.02). Parents rated physical functioning lower than adolescents (P<.0001), but there were no differences in psychosocial health. Adolescent PedsQL SS did not differ with diagnosis, but was inversely associated with adolescent body mass index z-score (P=.0004) and family conflict (P<.0001) and associated with race/ethnicity (P<.0001). Number of adolescent co-morbidities (P=.007) and burden of diabetes care (P<.05) were inversely associated with parent PedsQL SS. There were no differences in the Health Utilities Index-Mark 3 multi-attribute utility score.

conclusionsParents perceive their adolescents' physical functioning as more impaired than adolescents themselves. Contextual factors including severity of obesity, race/ethnicity, family conflict, and burden of diabetes care influence health-related quality of life. Family-based approaches to treatment and prevention of T2DM may benefit from increased attention to the biopsychosocial context.

Indexed as

Health StatusQuality of LifeAdolescentAdultAttitude to HealthChildDiabetes Mellitus, Type 2FemaleHumansIncidenceMalePrognosisPsychometricsRisk AssessmentRisk FactorsSurveys and Questionnaires

Identifiers

PMID22217471
PMCPMC4793715
OpenAlexW2001668167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.