Evidence map›Paper›PMID 22216772›Full record

Trial reportThe American journal of managed care2011

Use of health information technology to improve medication adherence.

William M Vollmer, Adrianne Feldstein, David H Smith, Joan P Dubanoski, Amy Waterbury, Jennifer L Schneider, Shelley A Clark, Cynthia Rand

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC
In one paragraph

Trial report in The American journal of managed care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00414817 (Phone Calls to Promote Adherence With Inhaled Corticosteroids), which is not on this map. Cited by 32 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00414817 nacompletednot on this map

Phone Calls to Promote Adherence With Inhaled Corticosteroids

TypeinterventionalSponsorKaiser PermanenteRan2007 to 2009Enrolled14,064ConditionsAsthmaArmsAutomated Phone-Based Refill Reminders
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  5. Interventions to improve adherence to inhaled steroids for asthma.The Cochrane database of systematic reviews · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

William M VollmerCenter for Health Research, 3800 N Interstate Ave., Portland, OR 97227-1110, USA. william.vollmer@kpchr.org
Adrianne Feldstein
David H Smith
Joan P Dubanoski
Amy Waterbury
Jennifer L Schneider
Shelley A Clark
Cynthia Rand

Funding

Use of Automated Phone Calls to Promote Adherence with Inhaled CorticosteroidsR01HL083433 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI VOLLMER, WILLIAM MARION · 2006 to 2009
$3.0M
NHLBI NIH HHS R01 HL083433NHLBI NIH HHS R01HL83433
6 · The paper itself

Abstract

objectivesTo evaluate the effectiveness of an intervention based on health information technology (HIT) that used speech recognition software to promote adherence to inhaled corticosteroids (ICS) among individuals with asthma who were members of a large health maintenance organization. STUDY

designPragmatic randomized clinical trial.

methodsAdults with asthma enrolled in a large managed care organization (N = 8517) were randomized to receive either usual care or an interactive voice recognition (IVR) intervention designed to prompt medication refills and improve ICS adherence. The primary outcome was ICS adherence as measured by modified medication possession ratio calculated from the electronic medical record (EMR). Secondary measures included survey- and EMR-based measures of asthma morbidity.

resultsOur primary analyses found that ICS adherence increased modestly but significantly for participants in the intervention group relative to those in the usual care group ( Δ= 0.02, 95% confidence interval 0.01-0.03), with a baseline adherence of 0.42 in both groups. No difference was observed in asthma morbidity measures. In post hoc analyses of participants receiving 2 or more direct IVR contacts or detailed messages, the intervention effect was more marked. The overall effect was triple that observed in the primary analyses (0.06 vs 0.02), and significant differences were observed between groups in asthma control.

conclusionsAn HIT-based adherence intervention shows potential for supporting medication adherence in patients with chronic diseases such as asthma. However, additional research is needed to determine how best to enhance the reach and effectiveness of such interventions.

Indexed as

Medication AdherenceAdministration, InhalationAdolescentAdrenal Cortex HormonesAdultAgedAged, 80 and overAnti-Asthmatic AgentsAsthmaConfidence IntervalsFemaleHealth PolicyHumansMaleManaged Care ProgramsMedical InformaticsAdrenal Cortex HormonesAnti-Asthmatic Agents

Identifiers

PMID22216772
PMCPMC3641901

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.