ArticleCardiovascular psychiatry and neurology2011
Depression, strokes and dementia: new biological insights into an unfortunate pathway.
Article in Cardiovascular psychiatry and neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Exploring the Complex Relationship Between Antidepressants, Depression and Neurocognitive Disorders.Biomedicines · 2024Review
- Rest-Activity Rhythm Characteristics Associated With Depression Symptoms in Stroke Survivors.Archives of physical medicine and rehabilitation · 2023Observational
- Ischemic stroke demographics, clinical features and scales and their correlations: an exploratory study from Jordan.Future science OA · 2022Article
- Perspectives on the complex links between depression and dementia.Frontiers in aging neuroscience · 2022Review
- Depression, dementia and immune dysregulation.Brain : a journal of neurology · 2021Article
- From Preclinical Stroke Models to Humans: Polyphenols in the Prevention and Treatment of Stroke.Nutrients · 2020Review
- The Role of Mast Cells in Stroke.Cells · 2019Review
- Depression may not be a risk factor for mortality in stroke patients with nonsurgical treatment: A retrospective case-controlled study.Medicine · 2019Article
- Is poststroke depression the same as major depression?Journal of psychiatry & neuroscience : JPN · 2018Article
- Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke.Translational psychiatry · 2016Article
- Neural effects of inflammation, cardiovascular disease, and HIV: Parallel, perpendicular, or progressive?Neuroscience · 2015Review
- Not all depression is created equal: sex interacts with disease to precipitate depression.Biology of sex differences · 2013Article
- Stroke prevention and cognitive reserve: emerging approaches to modifying risk and delaying onset of dementia.Frontiers in neurology · 2013Article
- The association between late-life depression, mild cognitive impairment and dementia: is inflammation the missing link?Expert review of neurotherapeutics · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The literature emphasizes the risk of depression after a stroke. Less well known is the fact that depression may be as big a risk factor for strokes as hypertension, particularly in the older age group. This article reviews the risk for stroke and cognitive impairment consequent to depression, and describes the cardiovascular and immunological mechanisms that would appear to link depression to its cerebrovascular consequences. As well, the article refers to the brain imaging signatures that may allow prediction of impending brain injury. Finally, some questions that might be explored by future research are suggested, and some practical means to identify and help those at risk for the development of depression-associated vascular disease of the brain are suggested.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.