ArticlePloS one2011
Genome-wide association study identifies candidate genes that affect plant height in Chinese elite maize (Zea mays L.) inbred lines.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
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59 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.
- Pooled it
- Identification of Potential Candidate Dwarf Genes in Maize by BSA-Seq and Transcriptomic Analyses.Plants (Basel, Switzerland) · 2026Article
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- Temporally resolved growth patterns reveal novel information about the polygenic nature of complex quantitative traits.The Plant journal : for cell and molecular biology · 2024Article
- Genome-wide association studies from spoken phenotypic descriptions: a proof of concept from maize field studies.G3 (Bethesda, Md.) · 2024Article
- Molecular markers and molecular basis of plant type related traits in maize.Frontiers in genetics · 2024Article
- Identification of Multiple Genetic Loci Related to Low-Temperature Tolerance during Germination in Maize (Current issues in molecular biology · 2023Article
- Identification of quantitative trait loci for related traits of stalk lodging resistance using genome-wide association studies in maize (Zea mays L.).BMC genomic data · 2022Article
- GWAS and RNA-seq analysis uncover candidate genes associated with alkaline stress tolerance in maize (Frontiers in plant science · 2022Article
- Genetics of Germination and Seedling Traits under Drought Stress in a MAGIC Population of Maize.Plants (Basel, Switzerland) · 2021Article
- Dissecting the Genetic Basis of Flowering Time and Height Related-Traits Using Two Doubled Haploid Populations in Maize.Plants (Basel, Switzerland) · 2021Article
- Mapping QTL/QTN and mining candidate genes for plant height and its response to planting densities in soybean [Molecular breeding : new strategies in plant improvement · 2021Article
- Dissecting the phenotypic components and genetic architecture of maize stem vascular bundles using high-throughput phenotypic analysis.Plant biotechnology journal · 2021Article
- QTL mapping and GWAS for field kernel water content and kernel dehydration rate before physiological maturity in maize.Scientific reports · 2020Article
- Identification of candidate tolerance genes to low-temperature during maize germination by GWAS and RNA-seqapproaches.BMC plant biology · 2020Article
- Genetic Architecture of Early Vigor Traits in Wild Soybean.International journal of molecular sciences · 2020Article
- Genome-Wide Association Study of Maize Aboveground Dry Matter Accumulation at Seedling Stage.Frontiers in genetics · 2020Article
- Identification of genetic loci and candidate genes related to soybean flowering through genome wide association study.BMC genomics · 2019Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe harvest index for many crops can be improved through introduction of dwarf stature to increase lodging resistance, combined with early maturity. The inbred line Shen5003 has been widely used in maize breeding in China as a key donor line for the dwarf trait. Also, one major quantitative trait locus (QTL) controlling plant height has been identified in bin 5.05-5.06, across several maize bi-parental populations. With the progress of publicly available maize genome sequence, the objective of this work was to identify the candidate genes that affect plant height among Chinese maize inbred lines with genome wide association studies (GWAS). METHODS AND
findingsA total of 284 maize inbred lines were genotyped using over 55,000 evenly spaced SNPs, from which a set of 41,101 SNPs were filtered with stringent quality control for further data analysis. With the population structure controlled in a mixed linear model (MLM) implemented with the software TASSEL, we carried out a genome-wide association study (GWAS) for plant height. A total of 204 SNPs (P≤0.0001) and 105 genomic loci harboring coding regions were identified. Four loci containing genes associated with gibberellin (GA), auxin, and epigenetic pathways may be involved in natural variation that led to a dwarf phenotype in elite maize inbred lines. Among them, a favorable allele for dwarfing on chromosome 5 (SNP PZE-105115518) was also identified in six Shen5003 derivatives.
conclusionsThe fact that a large number of previously identified dwarf genes are missing from our study highlights the discovery of the consistently significant association of the gene harboring the SNP PZE-105115518 with plant height (P=8.91e-10) and its confirmation in the Shen5003 introgression lines. Results from this study suggest that, in the maize breeding schema in China, specific alleles were selected, that have played important roles in maize production.
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