Evidence map›Paper›PMID 22216079›Full record

ArticleThe open neuroimaging journal2011

Magnetic resonance characterization of ischemic tissue metabolism.

Jerry S Cheung, Xiaoying Wang, Phillip Zhe Sun

Open access · hybridAbstract read
In one paragraph

Article in The open neuroimaging journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jerry S CheungAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Xiaoying Wang
Phillip Zhe Sun
Massachusetts General Hospital · USAthinoula A. Martinos Center for Biomedical Imaging · US

Funding

Quantitate and validate an endogenous ph magnetic resonance imaging techniqueK01EB009771 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI SUN, PHILLIP ZHE · 2009 to 2013
$873k
Translation of pH-weighted MRI to Image Human Acute StrokeR21NS061119 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, A. GREGORY · 2008 to 2009
$407k
NIBIB NIH HHS K01 EB009771NINDS NIH HHS R21 NS061119
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) and spectroscopy (MRS) are versatile diagnostic techniques capable of characterizing the complex stroke pathophysiology, and hold great promise for guiding stroke treatment. Particularly, tissue viability and salvageability are closely associated with its metabolic status. Upon ischemia, ischemic tissue metabolism is disrupted including altered metabolism of glucose and oxygen, elevated lactate production/accumulation, tissue acidification and eventually, adenosine triphosphate (ATP) depletion and energy failure. Whereas metabolism impairment during ischemic stroke is complex, it may be monitored non-invasively with magnetic resonance (MR)-based techniques. Our current article provides a concise overview of stroke pathology, conventional and emerging imaging and spectroscopy techniques, and data analysis tools for characterizing ischemic tissue damage.

Indexed as

cerebral ischemiametabolism.MRIMRSstroke

Identifiers

PMID22216079
PMCPMC3245409
OpenAlexW2161589202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.