Evidence map›Paper›PMID 22215941›Full record

ArticleWorld journal of gastroenterology2011

Five methods for detection of Helicobacter pylori in the Turkish population.

Orhan Cem Aktepe, Ihsan Hakkı Ciftçi, Birol Safak, Ihsan Uslan, Fatma Hüsniye Dilek

Abstract readEvaluation Study
In one paragraph

Article in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Non-invasive diagnostic tests for Helicobacter pylori infection.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Accuracy of gastric nodule combined with rapid urease test prediction in diagnosing Helicobacter pylori infection in children.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
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  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Orhan Cem AktepeDepartment of Microbiology, Faculty of Medicine, Afyon Kocatepe University, Ali Çetinkaya Campus, 03200 Afyonkarahisar, Turkey. aktepef@hotmail.com
Ihsan Hakkı Ciftçi
Birol Safak
Ihsan Uslan
Fatma Hüsniye Dilek

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare culture analysis, Helicobacter pylori (H. pylori) stool antigen (HpSA) test, polymerase chain reaction (PCR) and fluorescence in situ hybridization (FISH) for H. pylori detection.

methodsOne hundred and thirty-two consecutive adult dyspeptic patients receiving diagnostic endoscopy at the department of gastroenterology were enrolled in this study. Culture and histological examination were performed on biopsy specimens. PCR and FISH tests were applied to histopathological samples. Stool samples that were simultaneously collected were tested for the H. pylori antigen using the HpSA test and bacterial DNA using stool PCR.

resultsH. pylori was positively identified by histological examination in 85/132 (64.4%) of the patients, while positive samples were found in 56 (42.4%), 64 (48.5%), 98 (74.2%), 28 (21.2%) and 81 (61.4%) of the patients by culture, HpSA, PCR, stool PCR and FISH methods, respectively. The results of the culture, biopsy PCR, HpSA and FISH tests, with the exception of the stool PCR, were found to correlate with the histological examination as a gold standard.

conclusionThe HpSA test is a rapid, simple, and noninvasive test for monitoring therapy. FISH is an accurate, rapid, cost-effective, and easy-to-use test for H. pylori detection.

Indexed as

AdultAntigens, BacterialDiagnostic Tests, RoutineFecesHelicobacter InfectionsHelicobacter pyloriHumansIn Situ Hybridization, FluorescencePolymerase Chain ReactionTurkeyAntigens, BacterialFluorescence in situ hybridizationHelicobacter pyloriHelicobacter pylori stool antigenHistologyPolymerase chain reaction

Identifiers

PMID22215941
PMCPMC3243883

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.