Evidence map›Paper›PMID 22215901›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2012

Elusive extranuclear estrogen receptors in breast cancer.

Ellis R Levin

Open access · bronzeAbstract readComment
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. The Emerging Role ofCancers · 2019
    Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ellis R LevinDivision of Endocrinology, Department of Medicine, University of California, Irvine, Irvine, California, USA. ellis.levin@va.gov
University of California, Irvine · US

Funding

Non-genomic actions of estrogen in breast cancerR01CA100366 · NCI · SOUTHERN CALIFORNIA INST FOR RES/EDUC · PI LEVIN, ELLIS R · 2004 to 2014
$2.3M
NCI NIH HHS R01 CA100366
6 · The paper itself

Abstract

Estrogen receptors at the plasma membrane and cytoplasm have been difficult to detect in breast cancer specimens. New imaging approaches are needed to determine the percentage of cancers expressing extranuclear estrogen receptors and their impact on cancer biology and treatment.

Indexed as

Breast NeoplasmsCytoplasmEstrogen Receptor alphaFemaleHumansESR1 protein, humanEstrogen Receptor alpha

Identifiers

PMID22215901
PMCPMC3257555
OpenAlexW2171322788

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.