Evidence map›Paper›PMID 22215887›Full record

ArticleThe British journal of radiology2012

Clinical utility of ¹⁸F FDG-PET/CT in the detection of bone marrow disease in Hodgkin's lymphoma.

S Muzahir, M Mian, I Munir, M K Nawaz, Z S Faruqui, K A Mufti, H Bashir, N Uddin, N Siddiqui, A U R Maaz and 1 more

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in The British journal of radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Comparison of Bone Marrow Involvement with Bone Marrow Biopsy and PET-CT and Evaluation of Any Effects on Survival in Patients Diagnosed with Hodgkin and Non-Hodgkin Lymphoma.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2021
    Article
  3. Article
  4. European journal of nuclear medicine and molecular imaging · 2017
    Article
  5. Efficacy ofMolecular imaging and radionuclide therapy · 2017
    Article
  6. Article
  7. Review
  8. Characterizing bone marrow involvement in Hodgkin's lymphoma by FDG-PET/CT.European journal of nuclear medicine and molecular imaging · 2014
    Article
  9. Current role of FDG PET/CT in lymphoma.European journal of nuclear medicine and molecular imaging · 2014
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

S MuzahirDepartment of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital & Research Center, Lahore, Pakistan. syma_amer@yahoo.com
M Mian
I Munir
M K Nawaz
Z S Faruqui
K A Mufti
H Bashir
N Uddin
N Siddiqui
A U R Maaz
M T Mahmood
Shaukat Khanum Memorial Cancer Hospital and Research Center · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the study was to evaluate the potential role of fludeoxyglucose (FDG)-positron emission tomography (PET)/CT in the detection of bone/bone marrow disease in patients with Hodgkin's lymphoma (HL).

methodsWe retrospectively reviewed ((18)F)-FDG-PET/CT scans of 122 newly diagnosed, biopsy-proven cases of HL performed between November 2009 and June 2010. All the patients were staged before treatment by both PET/CT and bone marrow biopsy (BMB). Patients were subdivided into three groups based on the findings of FDG-PET/CT. Group A consisted of patients showing diffuse FDG uptake, Group B consisted of patients showing unifocal FDG uptake and Group C patients showed multifocal FDG-avid foci on PET/CT scans. Bone marrow results were also reviewed and considered positive if lymphomatous involvement was detected on bone marrow trephine biopsy. BMB results were correlated with FDG-PET/CT findings.

resultsThere were 122 patients in total-81 (66.4%) were male and 41 (33.6%) were female. The age range was from 6 years to 78 years (mean 35.70 years). PET/CT was reported as negative for bone/bone marrow involvement in 85 (69.7%) patients, while the remaining 37 showed abnormal FDG uptake. The sensitivity of FDG-PET/CT was calculated to be 100%, the specificity was 76.57%, the negative predictive value was 76.57%, the positive predictive value was 29.72% and the diagnostic accuracy was 78.62%.

conclusion(18)F-FDG-PET/CT and BMB are complementary in the evaluation of bone marrow disease.

Indexed as

Fluorodeoxyglucose F18Positron-Emission TomographyRadiopharmaceuticalsTomography, X-Ray ComputedAdolescentAdultAgedBone Marrow NeoplasmsChildFemaleHodgkin DiseaseHumansMaleMiddle AgedMultimodal ImagingRetrospective StudiesFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID22215887
PMCPMC3587106
OpenAlexW2111544864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.