ArticleMolecular & cellular proteomics : MCP2012
Quantitative proteomics reveals dynamic changes in the plasma membrane during Arabidopsis immune signaling.
Article in Molecular & cellular proteomics : MCP, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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52 citing papers in PubMed, 105 citations in OpenAlex.
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- Tandem Protein Kinases Emerge as New Regulators of Plant Immunity.Molecular plant-microbe interactions : MPMI · 2021Review
- Polycomb Repressive Complex 2 and KRYPTONITE regulate pathogen-induced programmed cell death in Arabidopsis.Plant physiology · 2021Article
- A novel allele of the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling.Genetics · 2021Article
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- The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.Plant physiology · 2020Article
- Plasma membrane receptor-like kinases and transporters are associated with 2,4-D resistance in wild radish.Annals of botany · 2020Article
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Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The plant plasma membrane is a crucial mediator of the interaction between plants and microbes. Understanding how the plasma membrane proteome responds to diverse immune signaling events will lead to a greater understanding of plant immunity and uncover novel targets for crop improvement. Here we report the results from a large scale quantitative proteomics study of plasma membrane-enriched fractions upon activation of the Arabidopsis thaliana immune receptor RPS2. More than 2300 proteins were identified in total, with 1353 proteins reproducibly identified across multiple replications. Label-free spectral counting was employed to quantify the relative protein abundance between different treatment samples. Over 20% of up-regulated proteins have known roles in plant immune responses. Significantly changing proteins include those involved in calcium and lipid signaling, membrane transport, primary and secondary metabolism, protein phosphorylation, redox homeostasis, and vesicle trafficking. A subset of differentially regulated proteins was independently validated during bacterial infection. This study presents the largest quantitative proteomics data set of plant immunity to date and provides a framework for understanding global plasma membrane proteome dynamics during plant immune responses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.