ArticleProceedings of the National Academy of Sciences of the United States of America2012
Glycosyl transferases in family 61 mediate arabinofuranosyl transfer onto xylan in grasses.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.
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109 citing papers in PubMed, 257 citations in OpenAlex.
- Multiplexed Engineering of Disease Resistance and Lodging Tolerance in Wheat Via a Single Xylan Modifying Glycosyltransferase.Plant biotechnology journal · 2026Article
- Crystal structure of epidermal growth factor domain-specificPNAS nexus · 2026Article
- Sex chromosome evolution mediated by a large inversion and a possible switch of the sex determination gene.Genome biology · 2026Article
- Fine-tuning xylan side chains for enhanced production of high-yield sugars, fine-shaped nanocrystals, and stable Pickering emulsions in Arabidopsis thaliana.Biotechnology for biofuels and bioproducts · 2026Article
- Enhancing maize resistance to Fusarium verticillioides through modulation of cell wall structure and components by ZmXYXT2.Journal of advanced research · 2025Article
- GT61 β-1,2-xylosyltransferases define a conserved xylan modification in gymnosperm and Arabidopsis primary cell walls.The Plant journal : for cell and molecular biology · 2025Article
- Cell wall-related glycosyltransferases and wall architecture in the model liverwort Marchantia polymorpha.The Plant journal : for cell and molecular biology · 2025Article
- Pangenomic and Phenotypic Characterization of ColombianInternational journal of molecular sciences · 2025Article
- Identification of universal grass genes and estimates of their monocot-/commelinid-/grass-specificity.Bioinformatics advances · 2025Article
- XYLAN O-ACETYLTRANSFERASE 6 promotes xylan synthesis by forming a complex with IRX10 and governs wall formation in rice.The Plant cell · 2024Article
- Heterogeneity in Mechanical Properties of Plant Cell Walls.Plants (Basel, Switzerland) · 2024Review
- Identification of glycosyltransferases mediating 2-O-arabinopyranosyl and 2-O-galactosyl substitutions of glucuronosyl side chains of xylan.The Plant journal : for cell and molecular biology · 2024Article
- The DEP1 Mutation Improves Stem Lodging Resistance and Biomass Saccharification by Affecting Cell Wall Biosynthesis in Rice.Rice (New York, N.Y.) · 2024Article
- Article
- Highly differentiated genomic properties underpin the different cell walls of Poaceae and eudicots.Plant physiology · 2023Article
- An update on xylan structure, biosynthesis, and potential commercial applications.Cell surface (Amsterdam, Netherlands) · 2023Review
- Genetic Approaches to Increase Arabinoxylan and β-Glucan Content in Wheat.Plants (Basel, Switzerland) · 2023Review
- Exploiting Rye in Wheat Quality Breeding: The Case of Arabinoxylan Content.Plants (Basel, Switzerland) · 2023Review
- The In Silico Characterization of Monocotyledonous α-l-Arabinofuranosidases on the Example of Maize.Life (Basel, Switzerland) · 2023Article
- NAC transcription factors ATAF1 and ANAC055 affect the heat stress response in Arabidopsis.Scientific reports · 2022Article
49 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
Abstract
Xylan, a hemicellulosic component of the plant cell wall, is one of the most abundant polysaccharides in nature. In contrast to dicots, xylan in grasses is extensively modified by α-(1,2)- and α-(1,3)-linked arabinofuranose. Despite the importance of grass arabinoxylan in human and animal nutrition and for bioenergy, the enzymes adding the arabinosyl substitutions are unknown. Here we demonstrate that knocking-down glycosyltransferase (GT) 61 expression in wheat endosperm strongly decreases α-(1,3)-linked arabinosyl substitution of xylan. Moreover, heterologous expression of wheat and rice GT61s in Arabidopsis leads to arabinosylation of the xylan, and therefore provides gain-of-function evidence for α-(1,3)-arabinosyltransferase activity. Thus, GT61 proteins play a key role in arabinoxylan biosynthesis and therefore in the evolutionary divergence of grass cell walls.
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