Mathematical modeling in immunotherapy of cancer: personalizing clinical trials.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed.

1. Mathematical modeling of the synergistic interplay of radiotherapy and immunotherapy in anti-cancer treatments.Frontiers in immunology · 2024
   Article
2. Opportunities for improving brain cancer treatment outcomes through imaging-based mathematical modeling of the delivery of radiotherapy and immunotherapy.Advanced drug delivery reviews · 2022
   Review
3. Chemoimmunotherapy Administration Protocol Design for the Treatment of Leukemia through Mathematical Modeling and In Silico Experimentation.Pharmaceutics · 2022
   Article
4. Optimal regulation of tumour-associated neutrophils in cancer progression.Royal Society open science · 2022
   Article
5. From Fitting the Average to Fitting the Individual: A Cautionary Tale for Mathematical Modelers.Frontiers in oncology · 2022
   Article
6. Systems Modeling to Quantify Safety Risks in Early Drug Development: Using Bifurcation Analysis and Agent-Based Modeling as Examples.The AAPS journal · 2021
   Review
7. Assessing the interactions between radiotherapy and antitumour immunity.Nature reviews. Clinical oncology · 2019
   Review
8. System-based approaches as prognostic tools for glioblastoma.BMC cancer · 2019
   Review
9. Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm.Journal of translational medicine · 2019
   Article
10. Learning-accelerated discovery of immune-tumour interactions.Molecular systems design & engineering · 2019
    Article
11. Alleviation of exhaustion-induced immunosuppression and sepsis by immune checkpoint blockers sequentially administered with antibiotics-analysis of a new mathematical model.Intensive care medicine experimental · 2019
    Article
12. Asymptotic dynamics of some t-periodic one-dimensional model with application to prostate cancer immunotherapy.Journal of mathematical biology · 2016
    Article
13. Computational oncology--mathematical modelling of drug regimens for precision medicine.Nature reviews. Clinical oncology · 2016
    Review
14. Differences in predictions of ODE models of tumor growth: a cautionary example.BMC cancer · 2016
    Article
15. Diagnostic assessment of osteosarcoma chemoresistance based on Virtual Clinical Trials.Medical hypotheses · 2015
    Article
16. Modeling cancer-immune responses to therapy.Journal of pharmacokinetics and pharmacodynamics · 2014
    Article
17. Estimating dose painting effects in radiotherapy: a mathematical model.PloS one · 2014
    Article
18. Mathematical model approach to describe tumour response in mice after vaccine administration and its applicability to immune-stimulatory cytokine-based strategies.The AAPS journal · 2013
    Article
19. Target-mediated disposition model describing the dynamics of IL12 and IFNγ after administration of a mifepristone-inducible adenoviral vector for IL-12 expression in mice.The AAPS journal · 2013
    Article
20. Personalizing immunotherapy: Balancing predictability and precision.Oncoimmunology · 2012
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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