ArticleBMC public health2012
Cell type specificity of female lung cancer associated with sulfur dioxide from air pollutants in Taiwan: an ecological study.
Article in BMC public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
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- Does the Level of Air Pollution Affect the Incidence of Lung Adenocarcinoma in South-Eastern Poland?International journal of environmental research and public health · 2023Article
- Incidence trends and spatial distributions of lung adenocarcinoma and squamous cell carcinoma in Taiwan.Scientific reports · 2023Article
- Environmental pollutants damage airway epithelial cell cilia: Implications for the prevention of obstructive lung diseases.Thoracic cancer · 2020Review
- Construction of polluted aerosol in accumulation that affects the incidence of lung cancer.Heliyon · 2020Article
- Associations between ambient air pollution and cancer incidence in Taiwan: an ecological study of geographical variations.BMC public health · 2019Article
- Estimating the spatial distribution of environmental suitability for female lung cancer mortality in China based on a novel statistical method.Environmental science and pollution research international · 2019Article
- A global perspective on coal-fired power plants and burden of lung cancer.Environmental health : a global access science source · 2019Article
- The association between ambient fine particulate matter and incident adenocarcinoma subtype of lung cancer.Environmental health : a global access science source · 2017Article
- A Water-Soluble Fluorescent Probe for SOJournal of fluorescence · 2017Article
- The clinicopathological and prognostic features of Chinese and Japanese inpatients with lung cancer.Oncotarget · 2016Article
- Perception of Air Pollution in the Jinchuan Mining Area, China: A Structural Equation Modeling Approach.International journal of environmental research and public health · 2016Article
- [Clinical Epidemiology and Histological Characteristics of 3,663 Lung Cancer Patients in Sichuan Province from 2008 to 2013].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2016Article
- Role of environmental pollutants in liver physiology: special references to peoples living in the oil drilling sites of Assam.PloS one · 2015Article
- Altered methylation in tandem repeat element and elemental component levels in inhalable air particles.Environmental and molecular mutagenesis · 2014Article
- Pathways enrichment analysis for differentially expressed genes in squamous lung cancer.Pathology oncology research : POR · 2014Article
- Indoor air pollution and risk of lung cancer among Chinese female non-smokers.Cancer causes & control : CCC · 2013Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany studies have examined the association between air pollutants (including sulfur dioxide [SO2], carbon monoxide [CO], nitrogen dioxide [NO2], nitric oxide [NO], ozone [O3], and particulate matter < 10 μm [PM10]) and lung cancer. However, data from previous studies on pathological cell types were limited, especially for SO2 exposure. We aimed to explore the association between SO2 exposure from outdoor air pollutants and female lung cancer incidence by cell type specificity.
methodsWe conducted an ecological study and calculated annual average concentration of 6 air pollutants (SO2, CO, NO2, NO, O3, and PM10) using data from Taiwan Environmental Protection Administration air quality monitoring stations. The Poisson regression models were used to evaluate the association between SO2 and age-standardized incidence rate of female lung cancer by two major pathological types (adenocarcinoma [AC] and squamous cell carcinoma [SCC]). In order to understand whether there is a dose-response relationship between SO2 and two major pathological types, we analyzed 4 levels of exposure based on quartiles of concentration of SO2.
resultsThe Poisson regression results showed that with the first quartile of SO2 concentration as the baseline, the relative risks for AC/SCC type cancer among females were 1.20 (95% confidence interval [CI], 1.04-1.37)/1.39 (95% CI, 0.96-2.01) for the second, 1.22 (95% CI, 1.04-1.43)/1.58 (95% CI, 1.06-2.37) for the third, and 1.27 (95% CI, 1.06-1.52)/1.80 (95% CI, 1.15-2.84) for the fourth quartile of SO2 concentration. The tests for trend were statistically significant for both AC and SCC at P = 0.0272 and 0.0145, respectively.
conclusionThe current study suggests that SO2 exposure as an air pollutant may increase female lung cancer incidence and the associations with female lung cancer is much stronger for SCC than for AC. The findings of this study warrant further investigation on the role of SO2 in the etiology of SCC.
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