ReviewProteomics. Clinical applications2012
The current Salmonella-host interactome.
Review in Proteomics. Clinical applications, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 62 citations in OpenAlex.
- Programmed cell death andFrontiers in microbiology · 2023Review
- The Salmonella T3SS1 effector IpaJ is regulated by ItrA and inhibits the MAPK signaling pathway.PLoS pathogens · 2022Article
- PHILM2Web: A high-throughput database of macromolecular host-pathogen interactions on the Web.Database : the journal of biological databases and curation · 2022Article
- Computational Network Inference for Bacterial Interactomics.mSystems · 2022Review
- Murine AML12 hepatocytes allow Salmonella Typhimurium T3SS1-independent invasion and intracellular fate.Scientific reports · 2021Article
- Analysis of In Vivo Transcriptome of Intracellular Bacterial PathogenPathogens (Basel, Switzerland) · 2021Article
- Tracking Pathogen Infections by Time-Resolved Chemical Proteomics.Angewandte Chemie (International ed. in English) · 2020Article
- In silico unravelling pathogen-host signaling cross-talks via pathogen mimicry and human protein-protein interaction networks.Computational and structural biotechnology journal · 2020Article
- CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection.Nature microbiology · 2019Article
- Campylobacteriosis, Salmonellosis, Yersiniosis, and Listeriosis as Zoonotic Foodborne Diseases: A Review.International journal of environmental research and public health · 2018Review
- Quantitative Proteomic Analysis Reveals Changes in the BenchmarkFrontiers in cellular and infection microbiology · 2017Article
- SalmoNet, an integrated network of tenNPJ systems biology and applications · 2017Article
- Live and inactivated Salmonella enterica serovar Typhimurium stimulate similar but distinct transcriptome profiles in bovine macrophages and dendritic cells.Veterinary research · 2016Article
- Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms.PLoS computational biology · 2015Article
- Reconstruction of the temporal signaling network in Salmonella-infected human cells.Frontiers in microbiology · 2015Article
- Comparing human-Salmonella with plant-Salmonella protein-protein interaction predictions.Frontiers in microbiology · 2015Article
- Techniques for transferring host-pathogen protein interactions knowledge to new tasks.Frontiers in microbiology · 2015Article
- Computational approaches for prediction of pathogen-host protein-protein interactions.Frontiers in microbiology · 2015Review
- Computational reconstruction of proteome-wide protein interaction networks between HTLV retroviruses and Homo sapiens.BMC bioinformatics · 2014Article
- Salmonella-how a metabolic generalist adopts an intracellular lifestyle during infection.Frontiers in cellular and infection microbiology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Salmonella bacteria cause millions of infections and thousands of deaths every year. This pathogen has an unusually broad host range including humans, animals, and even plants. During infection, Salmonella expresses a variety of virulence factors and effectors that are delivered into the host cell triggering cellular responses through protein-protein interactions (PPI) with host cell proteins which make the pathogen's invasion and replication possible. To speed up proteomic efforts in elucidating Salmonella-host interactomes, we carried out a survey of the currently published Salmonella-host PPI. Such a list can serve as the gold standard for computational models aimed at predicting Salmonella-host interactomes through integration of large-scale biological data sources. Manual literature and database search of >2200 journal articles and >100 databases resulted in a gold standard list of currently 62 PPI, including primarily interactions of Salmonella proteins with human and mouse proteins. Only six of these interactions were directly retrievable from PPI databases and 16 were highlighted in databases featuring literature extracts. Thus, the literature survey resulted in the most complete interactome available to date for Salmonella. Pathway analysis using Ingenuity and Broad Gene Set Enrichment Analysis (GSEA) software revealed among general pathways such as MAPK signaling in particular those related to cell death as well as cell morphology, turnover, and interactions, in addition to response to not only Salmonella but also other pathogenic - viral and bacterial - infections. The list of interactions is available at http://www.shiprec.org/indicationslist.htm.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.