Evidence map›Paper›PMID 22213412›Full record

ArticleAngewandte Chemie (International ed. in English)2012

Multiplex imaging of an intracellular proteolytic cascade by using a broad-spectrum nanoquencher.

Xinglu Huang, Magdalena Swierczewska, Ki Young Choi, Lei Zhu, Ashwinkumar Bhirde, Jinwoo Park, Kwangmeyung Kim, Jin Xie, Gang Niu, Kang Choon Lee and 2 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Chemical science · 2015
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Nanotheranostics for personalized medicine.Expert review of molecular diagnostics · 2013
    Review
  14. Article
  15. Review
  16. Real-time monitoring of caspase cascade activation in living cells.Journal of controlled release : official journal of the Controlled Release Society · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xinglu HuangLaboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, USA.
Magdalena Swierczewska
Ki Young Choi
Lei Zhu
Ashwinkumar Bhirde
Jinwoo Park
Kwangmeyung Kim
Jin Xie
Gang Niu
Kang Choon Lee
Seulki Lee
Xiaoyuan Chen

Funding

Laboratory of Molecular Imaging and NanomedicineZIAEB000073 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI CHEN, XIAOYUAN · 2010 to 2020
$32.8M
Development of preclinical HTS for discovery of drugs modulating apoptosisR00EB013450 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI LEE, SEULKI · 2013 to 2015
$718k
Nanoplatform-based combinational therapy against breast cancer R00CA153772 · NCI · UNIVERSITY OF GEORGIA · PI XIE, JIN · 2011 to 2013
$710k
Intramural NIH HHS Z99 EB999999Intramural NIH HHS ZIA EB000073NCI NIH HHS R00 CA153772NIBIB NIH HHS R00 EB013450
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CaspasesFluorescent DyesHCT116 CellsHumansMicellesMolecular StructureNanoparticlesNanotechnologyParticle SizePorosityProteolysisSilicon DioxideSurface PropertiesTime FactorsCaspasesFluorescent DyesMicellesSilicon Dioxide

Identifiers

PMID22213412
PMCPMC3622558

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.