ArticleMolecular genetics and genomics : MGG2012
Transcriptome analysis of rin mutant fruit and in silico analysis of promoters of differentially regulated genes provides insight into LeMADS-RIN-regulated ethylene-dependent as well as ethylene-independent aspects of ripening in tomato.
Article in Molecular genetics and genomics : MGG, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 51 citations in OpenAlex.
- Fruit-Specific Promoters in Plants: Advances, Regulatory Mechanisms and Applications in Plant Biotechnology.Plants (Basel, Switzerland) · 2026Review
- Comparative genomic analyses reveal different genetic basis of two types of fruit in Maloideae.Nature communications · 2025Article
- Transcriptome analysis reveals regulatory mechanism of postharvest softening in kiwiberry.BMC plant biology · 2024Article
- Dissection of mRNA acMolecular horticulture · 2024Article
- Transcriptional regulation of tomato fruit ripening.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- An overview of ethylene insensitive tomato mutants: Advantages and disadvantages for postharvest fruit shelf-life and future perspective.Frontiers in plant science · 2023Review
- Ethylene response factor ERF.D7 activates auxin response factor 2 paralogs to regulate tomato fruit ripening.Plant physiology · 2022Article
- Tissue-specific transcriptional regulation and metabolite accumulation in tomato (Solanum lycopersicum L.).Protoplasma · 2020Article
- Roles of RIN and ethylene in tomato fruit ripening and ripening-associated traits.The New phytologist · 2020Article
- Genome-wide analysis of genes encoding MBD domain-containing proteins from tomato suggest their role in fruit development and abiotic stress responses.Molecular biology reports · 2018Article
- A ripening-induced SlGH3-2 gene regulates fruit ripening via adjusting auxin-ethylene levels in tomato (Solanum lycopersicum L.).Plant molecular biology · 2018Article
- A comprehensive investigation of starch degradation process and identification of a transcriptional activator MabHLH6 during banana fruit ripening.Plant biotechnology journal · 2018Article
- Fruit preferential activity of the tomato RIP1 gene promoter in transgenic tomato and Arabidopsis.Molecular genetics and genomics : MGG · 2017Article
- Identification and expression profiling of DNA methyltransferases during development and stress conditions in Solanaceae.Functional & integrative genomics · 2016Article
- Seed development and viviparous germination in one accession of a tomato rin mutant.Breeding science · 2016Article
- Comprehensive Profiling of Ethylene Response Factor Expression Identifies Ripening-Associated ERF Genes and Their Link to Key Regulators of Fruit Ripening in Tomato.Plant physiology · 2016Article
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- Comprehensive Analysis of ABA Effects on Ethylene Biosynthesis and Signaling during Tomato Fruit Ripening.PloS one · 2016Article
- Fruit Ripening Regulation of α-Mannosidase Expression by the MADS Box Transcription Factor RIPENING INHIBITOR and Ethylene.Frontiers in plant science · 2016Article
- RNA sequencing and functional analysis implicate the regulatory role of long non-coding RNAs in tomato fruit ripening.Journal of experimental botany · 2015Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A thorough understanding of molecular mechanisms underlying ripening is the prerequisite for genetic manipulation of fruits for better shelf-life and nutritional quality. Mutation in LeMADS-RIN, a MADS-box gene, leads to non-ripening phenotype of rin fruits in tomato. Characterization of ripening-inhibitor (rin) mutant has elucidated important role of ethylene in the regulation of climacteric fruit ripening. A complete understanding of this mutation will unravel novel genetic regulatory mechanisms involved in fruit ripening. In this study, fruit transcriptomes of two genotypes, including a cultivated Indian cultivar Solanum lycopersicum cv. Pusa Ruby and a homozygous line harboring the rin mutation (LA1795) were compared to get better insight into RIN-regulated ethylene-dependent and ethylene-independent events during ripening. Cluster analysis of ripening-related genes indicated a major shift in their expression profiles in rin mutant fruit. A total of 112 genes, exhibiting expression patterns similar to that of LeMADS-RIN in wild-type fruits, showed down regulation of expression in the rin mutant. In silico analysis of putative promoters of these genes for the presence of CArG box along with ERE and ethylene inducibility of these genes revealed that genes lacking CArG box in their regulatory regions could be indirectly regulated by LeMADS-RIN. New regulators of ethylene-dependent aspect of ripening were also identified. In this study, we have made an attempt to distinguish between ethylene-dependent and ethylene-independent aspects of ripening, which will be useful for developing strategies to improve fruit-related agronomic traits in tomato and other crops.
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