Characterization of interactions between naturally mutated forms of the TIN2 protein and its known protein partners of the shelterin complex.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. A de novo TINF2, R282C Mutation in a Case of Dyskeratosis Congenital Founded by Next-Generation Sequencing.Iranian biomedical journal · 2023
   Article
2. A Truncating Germline Mutation ofThyroid : official journal of the American Thyroid Association · 2020
   Article
3. TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity.Molecular and cellular biology · 2019
   Article
4. The C-Terminal Extension Unique to the Long Isoform of the Shelterin Component TIN2 Enhances Its Interaction with TRF2 in a Phosphorylation- and Dyskeratosis Congenita Cluster-Dependent Fashion.Molecular and cellular biology · 2018
   Article
5. The molecular genetics of the telomere biology disorders.RNA biology · 2016
   Review
6. Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder.British journal of haematology · 2015
   Review
7. A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice.Genes & development · 2014
   Article
8. Molecular mechanisms of telomere biology disorders.The Journal of biological chemistry
   Review

Corrections and comments

• Comment on
  Three novel truncating TINF2 mutations causing severe dyskeratosis congenita in early childhood.2012

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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