ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2010
Fabrication and Characterization of Planar Plasmonic Substrates with High Fluorescence Enhancement.
Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- Plasmonic Ag/PMMA/Eu nanocomposite for sensitive dual mode detection of malachite green.Biomedical optics express · 2025Article
- Imaging optical fields below metal films and metal-dielectric waveguides by a scanning microscope.Journal of applied physics · 2017Article
- Surface-Enhanced Raman Scattering of Silicon Nanocrystals in a Silica Film.Scientific reports · 2016Article
- Several hundred-fold enhanced fluorescence from single fluorophores assembled on silver nanoparticle-dielectric-metal substrate.Chemical communications (Cambridge, England) · 2015Article
- Selectable Surface and Bulk Fluorescence Imaging with Plasmon-Coupled Waveguides.The journal of physical chemistry. C, Nanomaterials and interfaces · 2015Article
- Fluorescence Spectroscopy with Metal-Dielectric Waveguides.The journal of physical chemistry. C, Nanomaterials and interfaces · 2015Article
- Tamm State-Coupled Emission: Effect of Probe Location and Emission Wavelength.The journal of physical chemistry. C, Nanomaterials and interfaces · 2014Article
- Imaging of Protein Secretion from a Single Cell Using Plasmonic Substrates.BioNanoScience · 2013Article
- Large Fluorescence Enhancements of Fluorophore Ensembles with Multilayer Plasmonic Substrates: Comparison of Theory and Experimental Results.The journal of physical chemistry. C, Nanomaterials and interfaces · 2012Article
- Distance-Dependent Metal-Enhanced Intrinsic Fluorescence of Proteins Using Polyelectrolyte Layer-by-Layer Assembly and Aluminum Nanoparticles.The journal of physical chemistry. C, Nanomaterials and interfaces · 2012Article
- Silver-Gold Nanocomposite Substrates for Metal-Enhanced Fluorescence: Ensemble and Single-Molecule Spectroscopic Studies.The journal of physical chemistry. C, Nanomaterials and interfaces · 2012Article
- Fluorescence enhancement using silver-gold nanocomposite substrates.Proceedings of SPIE--the International Society for Optical Engineering · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The use of plasmonic nanostructures for fluorescence signal amplification is currently a very active research field. The detection of submonolayers of proteins labeled with organic dyes is a widely used technique in surface-based immunoassays and DNA hybridization. There is a strong interest in the development of new optical and chemical methods to increase the signal from ultralow concentrations of dyes on the surface of sensor substrates. Herein, we have explored the possibility of using vacuum-deposited silver nanostructures on dielectric layers and silver mirrors as potential plasmonic substrates that effectively amplify fluorescence over a broad spectral range. By optimizing deposition parameters for dielectric layers and silver nanostructures and applying thermal annealing processes, we observed large fluorescence amplifications from three different dye-strept(avidin) conjugates: about 7-fold for a UV/blue dye AF350-Av, 49-fold for a blue-green dye AF488-SA, and up to 208-fold for red-emitting AF647-SA dye. The observed amplification factors for the ensemble of fluorophores are very promising for development of surface-based bioassays. These substrates can be prepared using simple vacuum deposition in which we circumvent using the expensive nanofabrication methods. In addition, unlike most nanofabrication methods, the present approach is appropriate for large scale fabrication of substrates with microscope slide surface area suitable for sensing applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.