ArticleEukaryotic cell2012
Transcriptome and functional analysis of mating in the basidiomycete Schizophyllum commune.
Article in Eukaryotic cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 45 citations in OpenAlex.
- Morphogenesis, starvation, and light responses in a mushroom-forming fungus revealed by long-read sequencing and extensive expression profiling.Cell genomics · 2025Article
- Ectomycorrhizal Influence on the Dynamics of Sesquiterpene Release byJournal of fungi (Basel, Switzerland) · 2022Article
- Transcriptional response of mushrooms to artificial sun exposure.Ecology and evolution · 2021Article
- Inositol Signaling in the Basidiomycete FungusJournal of fungi (Basel, Switzerland) · 2021Article
- What Role Might Non-Mating Receptors Play inJournal of fungi (Basel, Switzerland) · 2021Article
- Phytohormones and volatile organic compounds, like geosmin, in the ectomycorrhiza of Tricholoma vaccinum and Norway spruce (Picea abies).Mycorrhiza · 2021Article
- Crosstalk between Ras and inositol phosphate signaling revealed by lithium action on inositol monophosphatase in Schizophyllum commune.Advances in biological regulation · 2019Article
- Nuclear arms races: Experimental evolution for mating success in the mushroom-forming fungus Schizophyllum commune.PloS one · 2018Article
- An Overview of the Function and Maintenance of Sexual Reproduction in Dikaryotic Fungi.Frontiers in microbiology · 2018Review
- Sexual selection in hermaphrodites, sperm and broadcast spawners, plants and fungi.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Hydrophobins in the Life Cycle of the Ectomycorrhizal Basidiomycete Tricholoma vaccinum.PloS one · 2016Article
- Comparative analysis of the secretomes of Schizophyllum commune and other wood-decay basidiomycetes during solid-state fermentation reveals its unique lignocellulose-degrading enzyme system.Biotechnology for biofuels · 2016Article
- Identification and functional analysis of pheromone and receptor genes in the B3 mating locus of Pleurotus eryngii.PloS one · 2014Article
- Review
- A central role for Ras1 in morphogenesis of the basidiomycete Schizophyllum commune.Eukaryotic cell · 2013Article
- The role of pheromone receptors for communication and mating in Hypocrea jecorina (Trichoderma reesei).Fungal genetics and biology : FG & B · 2012Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we undertook a functional characterization and transcriptome analysis that enabled a comprehensive study of the mating type loci of the mushroom Schizophyllum commune. Induced expression of both the bar2 receptor and the bap2(2) pheromone gene within 6 to 12 h after mates' contact was demonstrated by quantitative real-time PCR. Similar temporal expression patterns were confirmed for the allelic bbr1 receptor and bbp1 pheromone-encoding genes by Northern hybridization. Interestingly, the fusion of clamp connections to the subterminal cell was delayed in mating interactions in which one of the compatible partners expressed the bar2 receptor with a truncated C terminus. This developmental delay allowed the visualization of a green fluorescent protein (Gfp)-labeled truncated receptor at the cell periphery, consistent with a localization in the plasma membrane of unfused pseudoclamps. This finding does not support hypotheses envisioning a receptor localization to the nuclear membrane facilitating recognition between the two different nuclei present in each dikaryotic cell. Rather, Gfp fluorescence observed in such pseudoclamps indicated a role of receptor-pheromone interaction in clamp fusion. Transcriptome changes associated with mating interactions were analyzed in order to identify a role for pheromone-receptor interactions. We detected a total of 89 genes that were transcriptionally regulated in a mating type locus A-dependent manner, employing a cutoff of 5-fold changes in transcript abundance. Upregulation in cell cycle-related genes and downregulation of genes involved in metabolism were seen with this set of experiments. In contrast, mating type locus B-dependent transcriptome changes were observed in 208 genes, with a specific impact on genes related to cell wall and membrane metabolism, stress response, and the redox status of the cell.
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