Evidence map›Paper›PMID 22210637›Full record

ArticleAIDS (London, England)2012

Cellular immune responses and susceptibility to HIV-1 superinfection: a case-control study.

Catherine A Blish, Ozge C Dogan, Walter Jaoko, R Scott McClelland, Kishorchandra Mandaliya, Katherine S Odem-Davis, Barbra A Richardsonb, Julie Overbaugh

Abstract read
In one paragraph

Article in AIDS (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Frequency and implications of HIV superinfection.The Lancet. Infectious diseases · 2013
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Catherine A BlishDivision of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington, USA. cblish@stanford.edu
Ozge C Dogan
Walter Jaoko
R Scott McClelland
Kishorchandra Mandaliya
Katherine S Odem-Davis
Barbra A Richardsonb
Julie Overbaugh

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
INSTITUTE FOR TRANSLATIONAL HEALTH SCIENCE (UL1): BPCAUL1RR025014 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$51.5M
EARLY INFECTION IN WOMEN EXPOSED MUCOSALLY TO HIV-1R37AI038518 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI OVERBAUGH, JULIE M. · 1999 to 2019
$12.9M
Defining Immune Deficits in HIV-1 Infected WomenK08AI068424 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BLISH, CATHERINE A · 2006 to 2010
$597k
NCI NIH HHS P30 CA015704NCRR NIH HHS UL1 RR025014NIAID NIH HHS K08 AI068424NIAID NIH HHS P30 AI027757NIAID NIH HHS R37 AI038518NIAID NIH HHS R37-AI038518
6 · The paper itself

Abstract

A case-control study was performed to determine the effects of HIV-1-specific cellular immune responses on the odds of acquiring a second HIV-1 infection (superinfection). Changes in the frequency of cytokine-producing or cytolytic CD8+ or CD4+ T cells were not associated with significant alterations in the odds of superinfection, suggesting that HIV-1 specific cellular immune responses at the level induced by chronic infection do not appear to significantly contribute to protection from HIV-1 superinfection.

Indexed as

Case-Control StudiesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytokinesFemaleHIV-1HIV InfectionsHumansImmunity, CellularSuperinfectionCytokines

Identifiers

PMID22210637
PMCPMC3511787

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.