ReviewChemical senses2012
Chemesthesis and the chemical senses as components of a "chemofensor complex".
Review in Chemical senses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed.
- Review
- Diving Into the Chemical World of Cetaceans: A Review on the Chemical Senses in Dolphins and Whales.Journal of chemical ecology · 2026Review
- The S1-insula Circuit Differentially Modulates Alcohol Drinking and Aversive Behavior in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Chemosensory tobacco product toxicology part 1: sensory mechanisms.Toxicological sciences : an official journal of the Society of Toxicology · 2025Review
- Alcohol drinking is associated with greater calcium activity in mouse central amygdala dynorphin-expressing neurons.Progress in neuro-psychopharmacology & biological psychiatry · 2025Article
- Mouthfeel of Food and Beverages: A Comprehensive Review of Physiology, Biochemistry, and Key Sensory Compounds.Comprehensive reviews in food science and food safety · 2025Review
- The Expression of Cannabinoid and Cannabinoid-Related Receptors on the Gustatory Cells of the Piglet Tongue.Molecules (Basel, Switzerland) · 2024Article
- Association between Variants of the TRPV1 Gene and Body Composition in Sub-Saharan Africans.Genes · 2024Article
- Time-course of pain and salivary opiorphin release in response to oral capsaicin differ in burning mouth syndrome patients, temporomandibular disorders patients and control subjects.Clinical oral investigations · 2024Observational
- Sensory Nutrition and Bitterness and Astringency of Polyphenols.Biomolecules · 2024Review
- Smell, taste and chemesthesis disorders in patients with the SARS-CoV-2 during Omicron variant pandemic in China.Heliyon · 2023Article
- Trigeminal Function in Sino-Nasal Health and Disease.Biomedicines · 2023Review
- Pungency Perception and the Interaction with Basic Taste Sensations: An Overview.Foods (Basel, Switzerland) · 2023Review
- Examining the Influence of Chemosensation on Laryngeal Health and Disorders.Journal of voice : official journal of the Voice Foundation · 2023Review
- Varied Effects of COVID-19 Chemosensory Loss and Distortion on Appetite: Implications for Understanding Motives for Eating and Drinking.Foods (Basel, Switzerland) · 2022Article
- What Does the Taste System Tell Us About the Nutritional Composition and Toxicity of Foods?Handbook of experimental pharmacology · 2022Article
- Bitter Taste Disrupts Spatial Discrimination of Piperine-Evoked Burning Sensations: A Pilot Study.Biology · 2021Article
- Nutrigenomics reveals potential genetic underpinning of diverse taste preference of Chinese men.Genes & genomics · 2021Article
- The Fungiform Papilla Is a Complex, Multimodal, Oral Sensory Organ.Current opinion in physiology · 2021Article
- Interactions between Chemesthesis and Taste: Role of TRPA1 and TRPV1.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
An important function of the chemical senses is to warn against dangerous biological and chemical agents in the environment. The discovery in recent years of "taste" receptor cells outside the oral cavity that appear to have protective functions has raised new questions about the nature and scope of the chemical senses in general and of chemesthesis in particular. The present paper briefly reviews these findings within the context of what is currently known about the body's chemically sensitive protective mechanisms, including nonsensory processes that help to expel or neutralize threatening agents once they have been encountered. It is proposed that this array of defense mechanisms constitutes a "chemofensor complex" in which chemesthesis is the most ubiquitous, functionally diverse, and interactive chemosensory component.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.