ArticleSocial science & medicine (1982)2012
Social strain and cortisol regulation in midlife in the US.
Article in Social science & medicine (1982), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 70 citations in OpenAlex.
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- Social Support and Strain Amongst Early Childhood Educators: Insights from Experiences in the Workplace.Early childhood education journal · 2026Article
- Single status shows age dependent bidirectional effects in differentiated thyroid cancer.Scientific reports · 2025Article
- Early-Life Maternal Relationship Quality and Cognitive Function in Later Life: Mediating Role of Social Resources?The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Interpersonal, Community, and Societal Stressors Mediate Black-White Memory Disparities.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Increasing stress resilience in older adults through a 6-week prevention program: effects on coping strategies, anxiety symptoms, and cortisol levels.Frontiers in psychology · 2024Article
- Exposure to the Indian Ocean Tsunami shapes the HPA-axis resulting in HPA "burnout" 14 years later.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Social stress and risk of declining cognition: a longitudinal study of men and women in the United States.Social psychiatry and psychiatric epidemiology · 2022Article
- Childhood Stressors, Relationship Quality, and Cognitive Health in Later Life.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Daily Stressor Exposure and Daily Well-Being Among Sexual Minority and Heterosexual Adults in the United States: Results from the National Study of Daily Experiences (NSDE).Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022Article
- Theory of mind and hair cortisol in healthy young adults: the moderating effects of childhood trauma.European journal of psychotraumatology · 2022Article
- Associations between social burden, perceived stress, and diurnal cortisol profiles in older adults: implications for cognitive aging.European journal of ageing · 2021Article
- Gender differences in the relationship between social support and strain and mortality among a national sample of adults.Journal of behavioral medicine · 2021Article
- Covariation of psychobiological stress regulation with valence and quantity of social interactions in everyday life: disentangling intra- and interindividual sources of variation.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
- Recommendations for the Development of Socioeconomically-Situated and Clinically-Relevant Neuroimaging Models of Pain.Frontiers in neurology · 2021Article
- Minimally-invasive methods for examining biological changes in response to chronic stress: A scoping review.International journal of nursing studies · 2020Article
- Biomarking Trait Resilience With Salivary Cortisol in Chinese Undergraduates.Frontiers in psychology · 2020Review
- Social Integration and Quality of Social Relationships as Protective Factors for Inflammation in a Nationally Representative Sample of Black Women.Journal of urban health : bulletin of the New York Academy of Medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Chronic stress has been implicated in a variety of adverse health outcomes, from compromised immunity to cardiovascular disease to cognitive decline. The hypothalamic pituitary adrenal (HPA) axis has been postulated to play the primary biological role in translating chronic stress into ill health. Stressful stimuli activate the HPA-axis and cause an increase in circulating levels of cortisol. Frequent and long-lasting activation of the HPA-axis, as occurs in recurrently stressful environments, can in the long run compromise HPA-axis functioning and ultimately affect health. Negative social interactions with family and friends may be a significant source of stress in daily life, constituting the type of recurrently stressful environment that could lead to compromised HPA functioning and altered diurnal cortisol rhythms. We use data from two waves (1995 and 2004-2005) of the Midlife in the U.S. (MIDUS) study and from the National Study of Daily Experiences (NSDE) and piecewise growth curve models to investigate relationships between histories of social strain and patterns of diurnal cortisol rhythms. We find that reported levels of social strain were significantly associated with their diurnal cortisol rhythm. These effects were more pronounced for individuals with a history of greater reported strain across a ten-year period.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.