Evidence map›Paper›PMID 22209239›Full record

ReviewCurrent opinion in cell biology2012

Advances in light-based imaging of three-dimensional cellular ultrastructure.

Pakorn Kanchanawong, Clare M Waterman

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Modeling nonlinear optical microscopy in scattering media, part I. Propagation from lens to focal volume: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2023
    Article
  2. The extracellular matrix in tumor progression and metastasis.Clinical & experimental metastasis · 2019
    Review
  3. Neuropilins in the Context of Tumor Vasculature.International journal of molecular sciences · 2019
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Rapid computation of the amplitude and phase of tightly focused optical fields distorted by scattering particles.Journal of the Optical Society of America. A, Optics, image science, and vision · 2014
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pakorn KanchanawongNational Heart Lung and Blood Institute, Bethesda, MD, United States. biekp@nus.edu.sg
Clare M Waterman
National Heart Lung and Blood Institute · US

Funding

Intramural NIH HHS Z99 HL999999
6 · The paper itself

Abstract

Visualization methods are key to gaining insights into cellular structure and function. Since diffraction has long confined optical microscopes to a resolution no better than hundreds of nanometers, the observation of ultrastructural features has traditionally been the domain of electron microscopes (EM). In the past decade, however, advances in super-resolution fluorescence microscopy have considerably expanded the capability of light-based imaging techniques. Advantages of fluorescent labeling such as high sensitivity, specificity, and multichannel capability, can now be exploited to dissect ultrastructural features of cells. With recent methods capable of imaging specific proteins with a resolution on the order of a few tens of nanometers in 3-dimensions, this has made it possible to elucidate the molecular organization of many complex cellular structures.

Indexed as

CellsImaging, Three-DimensionalMicroscopy, ElectronMicroscopy, Fluorescence

Identifiers

PMID22209239
PMCPMC3294081
OpenAlexW2042228121

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.