ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2011
Comprehensive cardiovascular magnetic resonance of myocardial mechanics in mice using three-dimensional cine DENSE.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Measuring Cardiac Dyssynchrony with DENSE (Displacement Encoding with Stimulated Echoes)-A Systematic Review.Reviews in cardiovascular medicine · 2023Pooled it
- A validation of two-dimensional in vivo regional strain computed from displacement encoding with stimulated echoes (DENSE), in reference to tagged magnetic resonance imaging and studies in repeatability.Annals of biomedical engineering · 2014Trial
- Enhanced 2D Spiral Cine DENSE MRI Using Low-Rank Denoising for Improved Apparent Signal-to-Noise Ratio, Spatial Resolution, Efficiency, Accuracy, and Accessibility.Magnetic resonance in medicine · 2026Article
- Automated segmentation of the left-ventricle from MRI with a fully convolutional network to investigate CTRCD in breast cancer patients.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Can global longitudinal strain (GLS) with magnetic resonance prognosticate early cancer therapy-related cardiac dysfunction (CTRCD) in breast cancer patients, a prospective study?Magnetic resonance imaging · 2023Article
- Biomedical Imaging in Experimental Models of Cardiovascular Disease.Circulation research · 2022Review
- Direct left-ventricular global longitudinal strain (GLS) computation with a fully convolutional network.Journal of biomechanics · 2022Article
- A deep-learning semantic segmentation approach to fully automated MRI-based left-ventricular deformation analysis in cardiotoxicity.Magnetic resonance imaging · 2021Article
- Validation of a deep-learning semantic segmentation approach to fully automate MRI-based left-ventricular deformation analysis in cardiotoxicity.The British journal of radiology · 2021Article
- Comprehensive enhanced methodology of an MRI-based automated left-ventricular chamber quantification algorithm and validation in chemotherapy-related cardiotoxicity.Journal of medical imaging (Bellingham, Wash.) · 2020Article
- Fully automated and comprehensive MRI-based left-ventricular contractility analysis in post-chemotherapy breast cancer patients.The British journal of radiology · 2020Article
- MRI of Cardiotoxicity.Cardiology clinics · 2019Review
- Can post-chemotherapy cardiotoxicity be detected in long-term survivors of breast cancer via comprehensive 3D left-ventricular contractility (strain) analysis?Magnetic resonance imaging · 2019Article
- Quantification of regional right ventricular strain in healthy rats using 3D spiral cine dense MRI.Journal of biomechanics · 2019Article
- Introduction to a mechanism for automated myocardium boundary detection with displacement encoding with stimulated echoes (DENSE).The British journal of radiology · 2018Article
- Evaluation of a Novel Finite Element Model of Active Contraction in the Heart.Frontiers in physiology · 2018Article
- Regional quantification of myocardial mechanics in rat using 3D cine DENSE cardiovascular magnetic resonance.NMR in biomedicine · 2017Article
- Right Ventricular Strain, Torsion, and Dyssynchrony in Healthy Subjects Using 3D Spiral Cine DENSE Magnetic Resonance Imaging.IEEE transactions on medical imaging · 2017Article
- Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles.Circulation. Cardiovascular imaging · 2016Article
- Preliminary investigation of multiparametric strain Z-score (MPZS) computation using displacement encoding with simulated echoes (DENSE) and radial point interpretation method (RPIM).Journal of magnetic resonance imaging : JMRI · 2016Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundQuantitative noninvasive imaging of myocardial mechanics in mice enables studies of the roles of individual genes in cardiac function. We sought to develop comprehensive three-dimensional methods for imaging myocardial mechanics in mice.
methodsA 3D cine DENSE pulse sequence was implemented on a 7T small-bore scanner. The sequence used three-point phase cycling for artifact suppression and a stack-of-spirals k-space trajectory for efficient data acquisition. A semi-automatic 2D method was adapted for 3D image segmentation, and automated 3D methods to calculate strain, twist, and torsion were employed. A scan protocol that covered the majority of the left ventricle in a scan time of less than 25 minutes was developed, and seven healthy C57Bl/6 mice were studied.
resultsUsing these methods, multiphase normal and shear strains were measured, as were myocardial twist and torsion. Peak end-systolic values for the normal strains at the mid-ventricular level were 0.29 ± 0.17, -0.13 ± 0.03, and -0.18 ± 0.14 for E(rr), E(cc), and E(ll), respectively. Peak end-systolic values for the shear strains were 0.00 ± 0.08, 0.04 ± 0.12, and 0.03 ± 0.07 for E(rc), E(rl), and E(cl), respectively. The peak end-systolic normalized torsion was 5.6 ± 0.9°.
conclusionsUsing a 3D cine DENSE sequence tailored for cardiac imaging in mice at 7 T, a comprehensive assessment of 3D myocardial mechanics can be achieved with a scan time of less than 25 minutes and an image analysis time of approximately 1 hour.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.