ArticleFrontiers in pharmacology2011
Sulfur fumigation processing of traditional chinese medicinal herbs: beneficial or detrimental?
Article in Frontiers in pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The trial behind it
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Who cites it
20 citing papers in PubMed.
- Sulfur Fumigation-Induced Chemical Transformations in Lily Bulbs (Foods (Basel, Switzerland) · 2026Article
- Standardization and Development of Spray-Dried Chewable Tablets From the Traditional Thai Remedy "Ya-Tard Aob-Choei": HPLC Analysis and Comparison With Commercial Products.Advances in pharmacological and pharmaceutical sciences · 2026Article
- Sulfur fumigation of botanical drugs: impact on chemical composition and pharmacological properties, and advances in detection technologies.Frontiers in pharmacology · 2025Review
- Unveiling the Chemical Composition of Sulfur-Fumigated Herbs: A Triple Synthesis Approach Using UHPLC-LTQ-Orbitrap MS-A Case Study on Steroidal Saponins in Ophiopogonis Radix.Molecules (Basel, Switzerland) · 2024Article
- Biotransformation of Platycosides, Saponins from Balloon Flower Root, into Bioactive Deglycosylated Platycosides.Antioxidants (Basel, Switzerland) · 2023Review
- Article
- Production of Minor Ginsenoside CK from Major Ginsenosides by Biotransformation and Its Advances in Targeted Delivery to Tumor Tissues Using Nanoformulations.Nanomaterials (Basel, Switzerland) · 2022Review
- Comparison of the antioxidant activities of nonfumigated and sulphur-fumigatedPharmaceutical biology · 2021Article
- Glycyrrhizae Radix et Rhizoma Processed by Sulfur Fumigation Damaged the Chemical Profile Accompanied by Immunosuppression and Liver Injury.BioMed research international · 2020Article
- Treatment of Spleen-Deficiency Syndrome With Atractyloside A From Bran-ProcessedFrontiers in pharmacology · 2020Article
- A proposed protocol based on integrative metabonomics analysis for the rapid detection and mechanistic understanding of sulfur fumigation of Chinese herbal medicines.RSC advances · 2019Article
- Influence Factors of the Pharmacokinetics of Herbal Resourced Compounds in Clinical Practice.Evidence-based complementary and alternative medicine : eCAM · 2019Review
- Elucidation of Characteristic Sulfur-Fumigated Markers and Chemical Transformation Mechanism for Quality Control ofFrontiers in plant science · 2018Article
- Novelty application of multi-omics correlation in the discrimination of sulfur-fumigation and non-sulfur-fumigation Ophiopogonis Radix.Scientific reports · 2017Article
- Monitoring heavy metals, residual agricultural chemicals and sulfites in traditional herbal decoctions.BMC complementary and alternative medicine · 2017Article
- Review: DNA Barcoding and Chromatography Fingerprints for the Authentication of Botanicals in Herbal Medicinal Products.Evidence-based complementary and alternative medicine : eCAM · 2017Review
- Influence of sulfur fumigation on glycoside profile in Platycodonis Radix (Jiegeng).Chinese medicine · 2016Article
- Safety surveillance of traditional Chinese medicine: current and future.Drug safety · 2015Review
- Influence of sulfur fumigation on the chemical constituents and antioxidant activity of buds of Lonicera japonica.Molecules (Basel, Switzerland) · 2014Article
- Novel characterization of Radix Angelicae Dahuricae before and after the sulfur-fumigation process by combining high performance liquid chromatographic fingerprint and multi-ingredients determination.Pharmacognosy magazine · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Majority of traditional Chinese medicine (TCM) herbs need to undergo post-harvesting processing to convert raw material into the form readily used for prescription. In general, processing procedures are either according to China Pharmacopeia or based on traditional methods. Recently sulfur fumigation is increasingly used to replace traditional sun-drying for its pesticidal and anti-bacterial properties in a cheap and convenient manner. However, to date information on effects of sulfur fumigation on herbal safety and efficacy are limited. This article addresses potential destructive effects of sulfur fumigation on herbal efficacy and safety through reviewing currently available information. Since recently increased numbers of studies have demonstrated that sulfur fumigation-induced dramatic changes in chemical profiles of various sulfur-fumigated herbs, consequent alteration of efficacy, and/or potential incidence of toxicity are suspected. Therefore comprehensive investigations on effects of sulfur fumigation on toxicity, chemical profiles, pharmacokinetics, and bioactivities of TCM herbs are timely to provide scientific basis for standardization and regulation of this currently common but potentially harmful processing method.
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