ArticleMedical science monitor : international medical journal of experimental and clinical research2012
Attentional and emotional functioning in schizophrenia patients treated with conventional and atypical antipsychotic drugs.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Meta-analysis of Face Perception in Schizophrenia Spectrum Disorders: Evidence for Differential Impairment in Emotion Face Perception.Schizophrenia bulletin · 2024Pooled it
- A systematic review of the effects of psychiatric medications on social cognition.BMC psychiatry · 2021Pooled it
- Systematic Literature Review of the Methods Used to Compare Newer Second-Generation Agents for the Management of Schizophrenia: A focus on Health Technology Assessment.PharmacoEconomics · 2015Pooled it
- Facial emotion perception in schizophrenia: Does sex matter?World journal of psychiatry · 2016Article
- When does subliminal affective image priming influence the ability of schizophrenic patients to perceive face emotions?Medical science monitor : international medical journal of experimental and clinical research · 2014Article
- Dopamine beta-hydroxylase gene modulates individuals' empathic ability.Social cognitive and affective neuroscience · 2014Article
- The atypical antipsychotic risperidone reverses the recognition memory deficits induced by post-weaning social isolation in rats.Psychopharmacology · 2013Article
- Inferior performance on selected neuropsychological tests in abstinent schizophrenia patients who have used cannabis.Medical science monitor : international medical journal of experimental and clinical research · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEffectiveness of antipsychotics in treating emotional and cognitive deficits in schizophrenia still remains controversial. The aim of our study was to assess emotional and cognitive functioning in schizophrenic inpatients currently treated with typical antipsychotics (perphenazine, perazine, fluphenazine, and haloperidol) and in another group of schizophrenic inpatients currently on atypical antipsychotics (olanzapine, risperidone, amisulpride, and quetiapine). MATERIAL/
methodsOne hundred patients with DSM-IV schizophrenia or schizoaffective disorders (39 treated using typical antipsychotics and 61 treated with atypical antipsychotics) under naturalistic treatment conditions, and 50 healthy controls were given the following: Test of Everyday Attention, Facial Emotion Recognition Test, Facial Memory Recognition Test, and "Reading the mind in the eyes" Test.
resultsPatients with a diagnosis of schizophrenia revealed the following deficits: facial emotion perception, empathy /theory of mind, visual selective attention/speed, attentional switching, and auditory-verbal working memory. Our results show a significant difference between schizophrenic and healthy controls in all tasks, with schizophrenic patients performing worse than controls. Interestingly, our patients on atypical neuroleptics performed similarly compared to schizophrenic patients treated with conventional neuroleptics on all tasks provided. There were some significant relationships between emotional and cognitive deficits and clinical variables.
conclusionsOur findings remain consistent with other recent studies in which atypical antipsychotics did not show a clear advantage over typical antipsychotics on both emotional and cognitive functioning.
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