ArticleAnalytical chemistry2012
Constant flow-driven microfluidic oscillator for different duty cycles.
Article in Analytical chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 48 citations in OpenAlex.
- Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024Review
- Tunable resins with PDMS-like elastic modulus for stereolithographic 3D-printing of multimaterial microfluidic actuators.Lab on a chip · 2023Article
- Article
- Numerical Investigation of T-Shaped Microfluidic Oscillator with Viscoelastic Fluid.Micromachines · 2021Article
- A microfluidically controlled concave-convex membrane lens using an addressing operation system.Microsystems & nanoengineering · 2020Article
- A System for Analog Control of Cell Culture Dynamics to Reveal Capabilities of Signaling Networks.iScience · 2019Article
- Capacitive coupling synchronizes autonomous microfluidic oscillators.Electrophoresis · 2018Article
- Integrated Microfluidic Membrane Transistor Utilizing Chemical Information for On-Chip Flow Control.PloS one · 2016Article
- Multiple independent autonomous hydraulic oscillators driven by a common gravity head.Nature communications · 2015Article
- Pneumatic oscillator circuits for timing and control of integrated microfluidics.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Microfluidic oscillators with widely tunable periods.Lab on a chip · 2013Article
- Measurement of microchannel fluidic resistance with a standard voltage meter.Analytica chimica acta · 2013Article
- Analyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuits.Applied physics letters · 2012Article
- A mini-microscope for in situ monitoring of cells.Lab on a chip · 2012Article
- Microfluidic automation using elastomeric valves and droplets: reducing reliance on external controllers.Small (Weinheim an der Bergstrasse, Germany) · 2012Article
- Temporal gradients in microfluidic systems to probe cellular dynamics: a review.Analytica chimica acta · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
Abstract
This paper presents microfluidic devices that autonomously convert two constant flow inputs into an alternating oscillatory flow output. We accomplish this hardware embedded self-control programming using normally closed membrane valves that have an inlet, an outlet, and a membrane-pressurization chamber connected to a third terminal. Adjustment of threshold opening pressures in these 3-terminal flow switching valves enabled adjustment of oscillation periods to between 57 and 360 s with duty cycles of 0.2-0.5. These values are in relatively good agreement with theoretical values, providing the way for rational design of an even wider range of different waveform oscillations. We also demonstrate the ability to use these oscillators to perform temporally patterned delivery of chemicals to living cells. The device only needs a syringe pump, thus removing the use of complex, expensive external actuators. These tunable waveform microfluidic oscillators are envisioned to facilitate cell-based studies that require temporal stimulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.