ArticlePloS one2011
Analytical processing of binary mixture information by olfactory bulb glomeruli.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- How the olfactory bulb maintains stable odor manifolds amid adaptation and representational drift.bioRxiv : the preprint server for biology · 2026Article
- Imaging different cell populations in the mouse olfactory bulb using the genetically encoded voltage indicator ArcLight.Neurophotonics · 2024Review
- Article
- Disorder and the Neural Representation of Complex Odors.Frontiers in computational neuroscience · 2022Article
- Paradoxical relationship between speed and accuracy in olfactory figure-background segregation.PLoS computational biology · 2021Article
- Encoding innately recognized odors via a generalized population code.Current biology : CB · 2021Article
- Antagonistic odor interactions in olfactory sensory neurons are widespread in freely breathing mice.Nature communications · 2020Article
- Subpopulations of Projection Neurons in the Olfactory Bulb.Frontiers in neural circuits · 2020Review
- Similarity and Strength of Glomerular Odor Representations Define a Neural Metric of Sniff-Invariant Discrimination Time.Cell reports · 2019Article
- Learning-Dependent and -Independent Enhancement of Mitral/Tufted Cell Glomerular Odor Responses Following Olfactory Fear Conditioning in Awake Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- History-Dependent Odor Processing in the Mouse Olfactory Bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Control of Mitral/Tufted Cell Output by Selective Inhibition among Olfactory Bulb Glomeruli.Neuron · 2016Article
- Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding.PloS one · 2015Article
- Habituation of glomerular responses in the olfactory bulb following prolonged odor stimulation reflects reduced peripheral input.Frontiers in molecular neuroscience · 2015Article
- An olfactory cocktail party: figure-ground segregation of odorants in rodents.Nature neuroscience · 2014Article
- The perception of odor objects in everyday life: a review on the processing of odor mixtures.Frontiers in psychology · 2014Review
- Molecular events in the cell types of the olfactory epithelium during adult neurogenesis.Molecular brain · 2013Article
- Neural coding of binary mixtures in a structurally related odorant pair.Scientific reports · 2013Article
- Genetically encoded optical indicators for the analysis of neuronal circuits.Nature reviews. Neuroscience · 2012Review
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1 author.
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Abstract
Odors are rarely composed of a single compound, but rather contain a large and complex variety of chemical components. Often, these mixtures are perceived as having unique qualities that can be quite different than the combination of their components. In many cases, a majority of the components of a mixture cannot be individually identified. This synthetic processing of odor information suggests that individual component representations of the mixture must interact somewhere along the olfactory pathway. The anatomical nature of sensory neuron input into segregated glomeruli with the bulb suggests that initial input of odor information into the bulb is analytic. However, a large network of interneurons within the olfactory bulb could allow for mixture interactions via mechanisms such as lateral inhibition. Currently in mammals, it is unclear if postsynaptic mitral/tufted cell glomerular mixture responses reflect the analytical mixture input, or provide the initial basis for synthetic processing with the olfactory system. To address this, olfactory bulb glomerular binary mixture representations were compared to representations of each component using transgenic mice expressing the calcium indicator G-CaMP2 in olfactory bulb mitral/tufted cells. Overall, dorsal surface mixture representations showed little mixture interaction and often appeared as a simple combination of the component representations. Based on this, it is concluded that dorsal surface glomerular mixture representations remain largely analytical with nearly all component information preserved.
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