ReviewSensors (Basel, Switzerland)2010
Design strategies of fluorescent biosensors based on biological macromolecular receptors.
Review in Sensors (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 75 citations in OpenAlex.
- A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design.ACS sensors · 2026Article
- Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review.Advanced healthcare materials · 2026Review
- Advances in biosensors for bacterial detection and identification.World journal of microbiology & biotechnology · 2025Review
- A two-step screening to optimize the signal response of an auto-fluorescent protein-based biosensor.RSC advances · 2022Article
- Engineering a Fluorescent Protein Color Switch Using Entropy-Driven β-Strand Exchange.ACS sensors · 2022Article
- Fundamentals of Biosensors and Detection Methods.Advances in experimental medicine and biology · 2022Article
- Clinically oriented Alzheimer's biosensors: expanding the horizons towards point-of-care diagnostics and beyond.RSC advances · 2021Review
- Optical chemosensors for the detection of proximally phosphorylated peptides and proteins.RSC chemical biology · 2021Review
- Review
- Better together: building protein oligomers naturally and by design.Biochemical Society transactions · 2019Review
- The Advent of Salivary Breast Cancer Biomarker Detection Using Affinity Sensors.Sensors (Basel, Switzerland) · 2019Review
- Facile and Cost-Effective Detection of Saxitoxin Exploiting Aptamer Structural Switching.Food technology and biotechnology · 2015Article
- Review
- A signal-on fluorosensor based on quench-release principle for sensitive detection of antibiotic rapamycin.Biosensors · 2015Article
- Review
- Equilibrium and dynamic design principles for binding molecules engineered for reagentless biosensors.Analytical biochemistry · 2014Article
- Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.Analytical chemistry · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluorescent biosensors to detect the bona fide events of biologically important molecules in living cells are increasingly demanded in the field of molecular cell biology. Recent advances in the development of fluorescent biosensors have made an outstanding contribution to elucidating not only the roles of individual biomolecules, but also the dynamic intracellular relationships between these molecules. However, rational design strategies of fluorescent biosensors are not as mature as they look. An insatiable request for the establishment of a more universal and versatile strategy continues to provide an attractive alternative, so-called modular strategy, which permits facile preparation of biosensors with tailored characteristics by a simple combination of a receptor and a signal transducer. This review describes an overview of the progress in design strategies of fluorescent biosensors, such as auto-fluorescent protein-based biosensors, protein-based biosensors covalently modified with synthetic fluorophores, and signaling aptamers, and highlights the insight into how a given receptor is converted to a fluorescent biosensor. Furthermore, we will demonstrate a significance of the modular strategy for the sensor design.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.